Results 231 to 240 of about 74,680 (298)

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Predictors of Non-Cardiovascular Readmissions in Multimorbid Adults with Heart Failure in Australian Hospitals: A Retrospective Cohort Study. [PDF]

J Clin Med
Inglis JM, Caughey GE, Air T, Maddison J, Liew D, Shakib S.   +5 more
europepmc   +1 more source

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li, Yanwu Yang, Yan Zhang, Jirong Yue, Birong Dong, Meiling Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +7 more
wiley   +1 more source

Unsupervised Ensemble Learning for Active Drug-Induced Liver Injury Surveillance: Integrating Pharmacokinetic Burden With Enzyme Trajectories. [PDF]

Pharmacoepidemiol Drug Saf
Nakkaratniyom T, Hirunrassamee S, Boonchoo T, Sooksriwong CO.   +3 more
europepmc   +1 more source

Discontinuation of Glucagon‐Like Peptide‐1 Receptor Agonists After Bowel Obstruction or Ileus: A Nationwide, Real‐World, Database Study

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Objective Although concerns have been raised that glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) may increase the risk of bowel obstruction or ileus, evidence remains inconclusive. In this context of uncertainty, we examined the frequency and determinants of GLP‐1RA discontinuation after hospitalization for bowel obstruction/ileus ...
Yuichiro Matsuo, Akira Okada, Takashi Sakamoto, Hideo Yasunaga   +3 more
wiley   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li, Rui Liang, Birong Dong, Lunxu Liu, Ning Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +6 more
wiley   +1 more source

Development and Validation of an XGBoost-SHAP Model for Predicting Adverse Outcomes in Elderly Cardiovascular Patients With Polypharmacy: A Retrospective Cohort Study. [PDF]

Pharmacol Res Perspect
Wang K, Cao D.
europepmc   +1 more source

Applying a multidisciplinary intervention for drug adequacy in an intermediate care hospital (AMIDA-ICH): study protocol of a complex intervention trial. [PDF]

Front Med (Lausanne)
Salis F, Soler-Blanco N, Molist-Brunet N, Gual-Tarrada N, Ribera A, Cherubini A, Inzitari M, de Andrés-Lázaro AM.   +7 more
europepmc   +1 more source

Anticholinergic Burden at Admission and Discharge Among Geriatric Inpatients: A Single-Center Retrospective Cohort Study. [PDF]

Int J Gen Med
Akhtar A, Balquis F, Jamshed S, Asim Z, Sivanandy P, Mohamed Ibrahim MI, Aslam A, Arain MI, Iqbal A, Syed W, Al-Rawi MBA, Alqahtani N.   +11 more
europepmc   +1 more source