Results 21 to 30 of about 114,322 (384)

Association of polypharmacy and potential drug‐drug interactions with adverse treatment outcomes in older adults with advanced cancer

open access: yesCancer, 2023
Polypharmacy is common in older adults who are starting cancer treatment and is associated with an increased risk of potentially inappropriate medications (PIMs) and potential drug‐drug interactions (PDIs).
M. Mohamed   +9 more
semanticscholar   +1 more source

The Impact of Polypharmacy on the Effectiveness and Safety of Non-vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation

open access: yesThrombosis and Haemostasis, 2023
Background  Polypharmacy may affect outcomes in patients with atrial fibrillation (AF) using non-vitamin K antagonist oral anticoagulants (NOACs) or vitamin K antagonists (VKAs) due to interactions or reduced adherence, but comparative data are lacking ...
M. Grymonprez   +4 more
semanticscholar   +1 more source

Defining polypharmacy: in search of a more comprehensive determination method applied in a tertiary psychiatric hospital

open access: yesTherapeutic Advances in Psychopharmacology, 2021
Aims: This cross-sectional pharmacoepidemiologic study examined the prevalence of polypharmacy and psychotropic polypharmacy among inpatients in a tertiary psychiatric hospital in Belgium.
Jeroen Govaerts   +8 more
doaj   +1 more source

The effect of polypharmacy on healthcare services utilization in older adults with comorbidities: a retrospective cohort study

open access: yesBMC Primary Care, 2023
Background Older adults are more prone to increasing comorbidities and polypharmacy. Polypharmacy is associated with inappropriate prescribing and an increased risk of adverse effects.
George Doumat   +5 more
semanticscholar   +1 more source

An Increasing Trend in the Prevalence of Polypharmacy in Sweden: A Nationwide Register-Based Study

open access: yesFrontiers in Pharmacology, 2020
AimPolypharmacy is becoming a global health problem. The aims of this study were to evaluate the temporal trends in the prevalence of polypharmacy in Sweden and to explore polypharmacy disparities by age, gender, education, and immigration status ...
Naiqi Zhang   +7 more
doaj   +1 more source

Effect of Oral Anticoagulants in Atrial Fibrillation Patients with Polypharmacy: A Meta-analysis

open access: yesThrombosis and Haemostasis, 2023
Background  The aim of the present meta-analysis was to evaluate the effectiveness and safety of non-vitamin K antagonist oral anticoagulants (NOACs) versus vitamin K antagonists (VKAs) in atrial fibrillation (AF) patients with polypharmacy.
Yuxiang Zheng   +5 more
semanticscholar   +1 more source

DPSP: a multimodal deep learning framework for polypharmacy side effects prediction

open access: yesBioinformatics Advances, 2023
Motivation Because unanticipated drug–drug interactions (DDIs) can result in severe bodily harm, identifying the adverse effects of polypharmacy is one of the most important tasks in human health.
Raziyeh Masumshah, C. Eslahchi
semanticscholar   +1 more source

Sarcopenia is associated with a greater risk of polypharmacy and number of medications: a systematic review and meta‐analysis

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Polypharmacy in older adults is associated with multiple negative consequences that may affect muscular function, independently from the presence of medical conditions.
K. Prokopidis   +13 more
semanticscholar   +1 more source

The evolution of polypharmacy: appropriate and problematic polypharmacy, choosing the right strategy and tactics

open access: yesМедицинский совет, 2021
The evolution of polypharmacy, which for many years consisted of quantifying concurrently prescribed drugs, has led to an qualitative description: “appropriate polypharmacy”, which may be beneficial for some patients, and “problematic polypharmacy ...
M. V. Leonova
doaj   +1 more source

Global prevalence of polypharmacy and potentially inappropriate medication in older patients with dementia: a systematic review and meta-analysis

open access: yesFrontiers in Pharmacology, 2023
Background: Older patients with dementia always need multiple drugs due to comorbidities and cognitive impairment, further complicating drug treatment and increasing the risk of potentially inappropriate medication.
Mengnan Zhao   +4 more
semanticscholar   +1 more source

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