Results 41 to 50 of about 66,109 (299)

Optimizing medication use in older adults with multimorbidity and polypharmacy. [PDF]

, 2021
Background Globally, societies are ageing. In Switzerland, the population group of adults aged ≥ 65 years is projected to increase from around 17% in 2010 to a third of the population by the year 2050.
Jungo, Katharina Tabea
core  

Prevalence and determinants of polypharmacy in cardiovascular patients attending outpatient clinic in Ethiopia University Hospital.

PLoS ONE, 2020
BACKGROUND:While there are advances in medicine and pharmaceutical care, the burden of medication use has also grown with polypharmacy. In this regard, cardiovascular patients are subjected to polypharmacy for a longer period. OBJECTIVE:The present study
Yonas Getaye Tefera, Mekuriaw Alemayehu, Gashaw Binega Mekonnen   +2 more
doaj   +1 more source

Escalating polypharmacy [PDF]

QJM, 2006
New drug treatments, new indications for older drug treatments, lower thresholds for treating risk factors in preventative medicine, and an ageing population acquiring multiple pathologies all contribute to the development of polypharmacy. Longitudinal studies document the rise in prescribed medications, particularly in the elderly.
openaire   +2 more sources

Antipsychotic polypharmacy reduction versus polypharmacy continuation for people with schizophrenia [PDF]

, 2022
BACKGROUND: In clinical practice, different antipsychotics can be combined in the treatment of people with schizophrenia (polypharmacy). This strategy can aim at increasing efficacy, but might also increase the adverse effects due to drug–drug ...
Myrto T Samara, Stefan Leucht, Samara, Myrto T, Samara, Myrto T., Leucht, Stefan, Wulf-Peter Hansen, Ingrid Bauer, Cutrufelli, Pierfelice, Spyridon Siafis, Baeckers, Lio, Salvatore Salomone, Eugenio Aguglia, Bighelli, Irene, Siafis, Spyridon, Hansen, Wulf-Peter, Salomone, Salvatore, Aguglia, Eugenio, Bauer, Ingrid, Rodolico, Alessandro, Irene Bighelli, Pierfelice Cutrufelli, Alessandro Rodolico, Lio Baeckers   +22 more
core   +3 more sources

Defining pediatric polypharmacy: A scoping review.

PLoS ONE, 2018
ObjectivesLack of consensus regarding the semantics and definitions of pediatric polypharmacy challenges researchers and clinicians alike. We conducted a scoping review to describe definitions and terminology of pediatric polypharmacy.MethodsMedline ...
Paul M Bakaki, Alexis Horace, Neal Dawson, Almut Winterstein, Jennifer Waldron, Jennifer Staley, Elia M Pestana Knight, Sharon B Meropol, Rujia Liu, Hannah Johnson, Negar Golchin, James A Feinstein, Shari D Bolen, Lawrence C Kleinman   +13 more
doaj   +1 more source

In defence of polypharmacy [PDF]

British Journal of Clinical Pharmacology, 2004
The Greek word πολς (polus) had several meanings, such as many, mighty, and wide. The English prefix poly- usually takes the first of these meanings; polymyalgia means pain in many muscles, polyneuropathy disease of many nerves. However, πολς could also mean too much or too many. We all have many red blood cells, so polycythaemia means having too many;
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Variation of polypharmacy in older primary care attenders occurs at prescriber level

BMC Geriatrics, 2018
Background Polypharmacy is particularly important in older persons as they are more likely to experience adverse events compared to the rest of the population.
Su Miin Ong, Yvonne Mei Fong Lim, Sheamini Sivasampu, Ee Ming Khoo   +3 more
doaj   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Polypharmacy and associated factors in South Korean elderly patients with dementia: An analysis using National Health Insurance claims data.

PLoS ONE
BackgroundDementia is accompanied by several symptoms, including cognitive function decline, as well as behavioral and psychological symptoms. Elderly patients with dementia often experience polypharmacy, the concurrent use of multiple medications, due ...
Hea-Lim Kim, Hye-Jae Lee
doaj   +1 more source