Results 51 to 60 of about 66,109 (299)

Optimizing Hydroxychloroquine Blood Levels and Long‐Term Hydroxychloroquine Intake Could Lower ASCVD Risk and Prevent Polypharmacy in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Background Hydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematosus (SLE) management with benefits extending beyond SLE control, including protection against atherosclerotic cardiovascular disease (ASCVD). While HCQ blood levels reflect recent exposure and long‐term intake reflects medication adherence, the impact of longitudinal ...
Shivani Garg, Murray Urowitz, Charlie Dentz, Niriti Adhikari, Fauzia Hollnagel, Nathalie Costedoat‐Chalumeau   +5 more
wiley   +1 more source

Polypharmacy and excessive polypharmacy in community-dwelling middle aged and aged adults between 2011 and 2015 [PDF]

, 2021
AIMS: We aimed to assess the prevalence, components and evolution of polypharmacy and to evaluate risk factors associated with polypharmacy. METHODS: A retrospective dynamic cohort study was performed, using a primary healthcare database comprising ...
van den Akker, Marjan, van den Akker, M., Van Pottelbergh, G., Spriet, Isabel, Vaes, Bert, Hellemans, Laura, Van Pottelbergh, Gijs, Hias, Julie, Rygaert, Xavier, van der Linden, Lorenz, Nuyts, S., Tournoy, Jos, Hellemans, L., Nuyts, Shauni, Rygaert, X., Hias, J., Spriet, I., van der Linden, L., Tournoy, J., Vaes, B.   +19 more
core   +1 more source

Sleep Disturbances in Adults With Tuberous Sclerosis Complex: Influences of Treatment and Clinical Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Tuberous sclerosis complex (TSC) is a genetic condition with multisystem neurocutaneous signs, including hamartomas, epilepsy, and neuropsychological difficulties. Although sleep disorders are increasingly recognized in TSC, they remain poorly described in adults.
Kirstin A. Risgaard, Laura Farach, Hope Northrup, Sarah L. Wilson, Deborah Pearson, Syed Hashmi, Kate Richardson   +6 more
wiley   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis Within a Longitudinal Cohort

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Multi-Institutional Drug Use Patterns in Hospitalized Older Patients: Retrospective Cross-Sectional Study

JMIR Medical Informatics
BackgroundA rapidly aging population led to an increase in the number of patients with chronic diseases and polypharmacy. Although investigations on the appropriate number of drugs for older patients have been conducted, there is ...
Chung Chun Lee, Grace Juyun Kim, Suhyun Kim, Jee Young Hong, Won Min Hwang, Jong-Yeup Kim, Kye Hwa Lee, Kwangsoo Kim, Mingyu Kang, Ju Han Kim, Suehyun Lee   +10 more
doaj   +1 more source

Prevalence, association, and prognostic significance of polypharmacy and sarcopenia in patients with liver cirrhosis

JGH Open, 2023
Background and Aim Polypharmacy and sarcopenia are increasing public health problems worldwide. However, data on the prevalence, association, and prognostic significance of polypharmacy and sarcopenia in patients with liver cirrhosis are limited. Methods
Tatsunori Hanai, Kayoko Nishimura, Takao Miwa, Toshihide Maeda, Kenji Imai, Atsushi Suetsugu, Koji Takai, Masahito Shimizu   +7 more
doaj   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Polypharmacy, medication adherence and medication management at home in elderly patients with multiple non-communicable diseases in Thai primary care [PDF]

, 2017
Background . Polypharmacy among elderly patients in primary care settings is a global phenomenon that has not been well examined in Thailand. Objectives .
Viwat Puttawanchai, Pasitpon Vatcharavongvan, Puttawanchai, Viwat, Vatcharavongvan, Pasitpon   +3 more
core   +1 more source

Frailty and the Risk of Polypharmacy in the Older Person: Enabling and Preventative Approaches [PDF]

, 2020
Frail older people have an inherent risk of polypharmacy due to the need to treat multiple comorbidities, thus leading to various negative effects on their health due to the adverse actions from the drugs.
Nwadiugwu, Martin C, Martin C. Nwadiugwu
core   +1 more source

Prevalence and Predictors of Excessive Polypharmacy in Geriatric Inpatients: A Retrospective Cross-Sectional Study in Indonesia

Journal of Primary Care & Community Health, 2023
Objectives: To investigate the prevalence and predictors of excessive polypharmacy in geriatric inpatients in Indonesia. Methods: This retrospective cross-sectional study included 1533 inpatients over the age of 60 years at Universitas Airlangga Hospital,
Shah Faisal, Elida Zairina, Surakit Nathishuwan, Junaidi Khotib, Susi Ari Kristina, Gesnita Nugraheni   +5 more
doaj   +1 more source