Results 51 to 60 of about 74,680 (298)

Prevalence, association, and prognostic significance of polypharmacy and sarcopenia in patients with liver cirrhosis

open access: yesJGH Open, 2023
Background and Aim Polypharmacy and sarcopenia are increasing public health problems worldwide. However, data on the prevalence, association, and prognostic significance of polypharmacy and sarcopenia in patients with liver cirrhosis are limited. Methods
Tatsunori Hanai   +7 more
doaj   +1 more source

Optimizing Hydroxychloroquine Blood Levels and Long‐Term Hydroxychloroquine Intake Could Lower Atherosclerotic Cardiovascular Disease Risk and Prevent Polypharmacy in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematosus (SLE) management with benefits extending beyond SLE control, including protection against atherosclerotic cardiovascular disease (ASCVD). Although HCQ blood levels reflect recent exposure and long‐term intake reflects medication adherence, the impact of longitudinal ...
Shivani Garg   +5 more
wiley   +1 more source

In defence of polypharmacy [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2004
The Greek word πολς (polus) had several meanings, such as many, mighty, and wide. The English prefix poly- usually takes the first of these meanings; polymyalgia means pain in many muscles, polyneuropathy disease of many nerves. However, πολς could also mean too much or too many. We all have many red blood cells, so polycythaemia means having too many;
openaire   +2 more sources

Polypharmacy, medication adherence and medication management at home in elderly patients with multiple non-communicable diseases in Thai primary care [PDF]

open access: yes, 2017
Background . Polypharmacy among elderly patients in primary care settings is a global phenomenon that has not been well examined in Thailand. Objectives .
Viwat Puttawanchai   +3 more
core   +1 more source

Polypharmacy and excessive polypharmacy in community-dwelling middle aged and aged adults between 2011 and 2015 [PDF]

open access: yes, 2021
AIMS: We aimed to assess the prevalence, components and evolution of polypharmacy and to evaluate risk factors associated with polypharmacy. METHODS: A retrospective dynamic cohort study was performed, using a primary healthcare database comprising ...
van den Akker, Marjan   +19 more
core   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell   +2 more
wiley   +1 more source

Prevalence and Predictors of Excessive Polypharmacy in Geriatric Inpatients: A Retrospective Cross-Sectional Study in Indonesia

open access: yesJournal of Primary Care & Community Health, 2023
Objectives: To investigate the prevalence and predictors of excessive polypharmacy in geriatric inpatients in Indonesia. Methods: This retrospective cross-sectional study included 1533 inpatients over the age of 60 years at Universitas Airlangga Hospital,
Shah Faisal   +5 more
doaj   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Polypharmacy in Elderly: Overview, Prevalence and Psychiatric Perspectives

open access: yesJournal of the Indian Academy of Geriatrics, 2019
Introduction: Ageing is a natural phenomenon that is accompanied by a cascade of unwanted and unintended circumstances or problems that are always undesirable but not still avoidable.
Priya Sharma, P Khuda, N L Gupta
doaj   +1 more source

Diurnal effects of polypharmacy with high drug burden index on physical activities over 23 h differ with age and sex

open access: yesScientific Reports, 2022
Aging, polypharmacy (concurrent use of ≥ 5 medications), and functional impairment are global healthcare challenges. However, knowledge of the age/sex-specific effects of polypharmacy is limited, particularly on daily physical activities.
Trang Tran   +7 more
doaj   +1 more source

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