Results 41 to 50 of about 96,456 (293)

Variation of polypharmacy in older primary care attenders occurs at prescriber level

BMC Geriatrics, 2018
Background Polypharmacy is particularly important in older persons as they are more likely to experience adverse events compared to the rest of the population.
Su Miin Ong, Yvonne Mei Fong Lim, Sheamini Sivasampu, Ee Ming Khoo   +3 more
doaj   +1 more source

A Cross-Sectional Study Comparing the Frequency of Drug Interactions After Adding Simeprevir- or Sofosbuvir-Containing Therapy to Medication Profiles of Hepatitis C Monoinfected Patients. [PDF]

, 2015
INTRODUCTION:This study compares the expected occurrence of contraindicated drug-drug interactions (XDDIs) when simeprevir (SIM)- or sofosbuvir (SOF)-containing therapy is added to medication profiles of patients with hepatitis C (HCV) monoinfection to ...
Bliss, Steven, Davis, Melissa, Koroglu, Arden, McNutt, Louise-Anne, Miller, Christopher, Nasiri, Mona, Patel, Nimish   +6 more
core   +1 more source

RAB39B Related Parkinsonism in an Italian Family: A Unique Use of Advanced Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Parkinson's disease (PD) is a neurodegenerative disorder that may sometimes be caused by deleterious genetic variants. Among them, RAB39B polymorphisms are known as rare causes of early‐onset PD associated with intellectual disability (Waisman's syndrome).
Caterina Del Regno, Giovanni Ermanis, Christian Lettieri, Andrea Bernardini, Gaia Pellitteri, Enrico Belgrado, Elena Betto, Gian Luigi Gigli, David De Monte, Marco Domenico Scanni, Marco Mucchiut, Giuseppe Damante, Mariarosaria Valente, Francesco Janes   +13 more
wiley   +1 more source

Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool [PDF]

, 2016
Background: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP).
Boussery, Koen, Mattelin, Kristof, Mehuys, Els, PATTYN, EVA, Petrovic, Mirko, Somers, Annemie, Tommelein, Eline, Van Damme, Charlotte   +7 more
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Regional differences in the profile of disabled community-dwelling older adults: a European population-based cross-sectional study [PDF]

, 2018
The main objective of this work was to estimate the prevalence of disability in European community-dwelling older adults, as well as to investigate differences in the profile of disabled older adults between European regions (Northern, Central, Eastern ...
Bagur-Calafat , Caritat, Bezerra de Souza , Dyego L., Bosque-Prous , Marina, Espelt , Albert, Gine-Garriga, Maria, Jerez-Roig , Javier, Teixidó-Compañó , Ester   +6 more
core   +6 more sources

Radiation emergency medical countermeasures: Current formulary, identified gaps, and future approaches

Animal Models and Experimental Medicine, EarlyView.
Current radiation medical countermeasures primarily focus on hematopoietic acute radiation syndrome (H‐ARS) using agents like granulocyte colony‐stimulating factor (G‐CSF), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), and romiplostim, alongside treatments for internal contamination (Prussian blue, diethylenetriamine pentaacetate [DTPA ...
Wen‐Bing Ma, Rong‐Hua Yin, Guang‐Ming Ren, Yin Zhang, Li‐Juan Li, Wei Liu, Ting Chen, Wei Zhou, Mian Zu, Rong‐Ling Yin, Xin‐Di Shi, Lei Wang, Xiao‐Ming Yang   +12 more
wiley   +1 more source

Polypharmacy and associated factors in South Korean elderly patients with dementia: An analysis using National Health Insurance claims data.

PLoS ONE
BackgroundDementia is accompanied by several symptoms, including cognitive function decline, as well as behavioral and psychological symptoms. Elderly patients with dementia often experience polypharmacy, the concurrent use of multiple medications, due ...
Hea-Lim Kim, Hye-Jae Lee
doaj   +1 more source

Polypharmacy in Elderly: Overview, Prevalence and Psychiatric Perspectives

Journal of the Indian Academy of Geriatrics, 2019
Introduction: Ageing is a natural phenomenon that is accompanied by a cascade of unwanted and unintended circumstances or problems that are always undesirable but not still avoidable.
Priya Sharma, P Khuda, N L Gupta
doaj   +1 more source

Prevalence and trends of polypharmacy in U.S. adults, 1999–2018

Global Health Research and Policy, 2023
Background Polypharmacy is one of the most important health issues for its potential impacts on disease burden and healthcare costs. The aim of this study was to update a comprehensive picture of prevalence and trends in polypharmacy over 20 years in U.S.
Xiaowen Wang, Keyang Liu, Kokoro Shirai, Chengyao Tang, Yonghua Hu, Ying Wang, Yuantao Hao, Jia-Yi Dong   +7 more
doaj   +1 more source