Results 81 to 90 of about 99,805 (324)

Clinician's attitudes & perspective on chemical adherence testing in hypertension (CATCH): A qualitative interview study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Chemical Adherence Testing (CAT) is gaining prominence as a reliable and valid clinical method to detect whether antihypertensive agents are being taken as prescribed. This study aimed to explore clinicians' attitudes and perspectives on the clinical use of CAT.
Roshan Shahab, Louise Rabbitt, Gerard J. Molloy   +2 more
wiley   +1 more source

Polypharmacy in primary care: A population-based retrospective cohort study of electronic health records.

PLoS ONE
BackgroundPolypharmacy, prescription of multiple medications to a patient, is a major challenge for health systems. There have been no peer-reviewed studies of polypharmacy prevalence and medication cost at a population level in England.AimsTo determine ...
Thomas Woodcock, Derryn Lovett, Gloria Ihenetu, Vesselin Novov, Thomas Beaney, Keivan Armani, Angela Quilley, Azeem Majeed, Paul Aylin   +8 more
doaj   +1 more source

Antipsychotic Polypharmacy among Children and Young Adults in Office-Based or Hospital Outpatient Department Settings

Pharmacy, 2017
The purpose of the study was three-fold: (1) to estimate the national trends in antipsychotic (AP) polypharmacy among 6- to 24-year-old patients in the U.S.; (2) to identify frequently used AP agents and mental disorder diagnoses related to AP ...
Minji Sohn, Meghan Burgess, Mohamed Bazzi   +2 more
doaj   +1 more source

Prevalence of polypharmacy and associated adverse health outcomes in adult patients with chronic kidney disease: protocol for a systematic review and meta-analysis

Systematic Reviews, 2021
Background Polypharmacy, often defined as the concomitant use of ≥ 5 medications, has been identified as a significant global public health threat. Aging and multimorbidity are key drivers of polypharmacy and have been linked to a broad range of adverse ...
Ikechi G. Okpechi, Mohammed M. Tinwala, Shezel Muneer, Deenaz Zaidi, Feng Ye, Laura N. Hamonic, Maryam Khan, Naima Sultana, Scott Brimble, Allan Grill, Scott Klarenbach, Cliff Lindeman, Amber Molnar, Dorothea Nitsch, Paul Ronksley, Soroush Shojai, Boglarka Soos, Navdeep Tangri, Stephanie Thompson, Delphine Tuot, Neil Drummond, Dee Mangin, Aminu K. Bello   +22 more
doaj   +1 more source

Physiological monitoring in the complex multimorbid heart failure patient - Conclusions. [PDF]

, 2019
Comorbidities are increasingly recognized as crucial components of the heart failure syndrome. Main specific challenges are polypharmacy, poor adherence to treatments, psychological aspects, and the need of monitoring after discharge.
Böhm, M, Coats, AJS, Kindermann, I, Rosano, G, Spoletini, I   +4 more
core   +1 more source

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

Preva Lence Of Quantitative And Qualitative Polypharmacy In Older Adults With Alzheimer Dementia [PDF]

Geriatrics, Gerontology and Aging
BACKGROUND: Polypharmacy can be defined quantitatively or qualitatively. One of the concepts underlying the quantitative definition of polypharmacy is the use of two or more medications.
Patrícia Medeiros de Souza, Liana Tieko Evangelista Kusano, Leopoldo Luiz dos Santos Neto   +2 more
doaj   +1 more source

Influences of Body Composition, Multimorbidity and Polypharmacy on Physical Mobility of Older Adults

, 2016
Background and Purpose: The prevalence of falls, and the resulting injuries and complications reflect a key concern in the older adult population. An increased risk of falls is highly correlated with decreases in physical mobility and related functions ...
Chen, Chieh, Sestini, Linna, Wilde, Rachel   +2 more
core   +1 more source

Potentially inappropriate medication in older participants of the Berlin Aging Study II (BASE-II) - Sex differences and associations with morbidity and medication use [PDF]

, 2019
INTRODUCTION: Multimorbidity in advanced age and the need for drug treatment may lead to polypharmacy, while pharmacokinetic and pharmacodynamic changes may increase the risk of adverse drug events (ADEs).
A Calderon-Larranaga, A Meyer, A Renom-Guiteras, B Pesch, By the American Geriatrics Society Beers Criteria Update Expert P, C Coupland, C. Walker, CE Leonard, CH Vinkers, D Gerstorf, D O'Mahony, DM Fick, DM Nathan, E Sonnerstam, E Tommelein, Elisabeth Steinhagen-Thiessen, FR Motter, GE Miller, Gianluigi Forloni, HG Endres, I Schubert, Ilja Demuth, Juliane Bolbrinker, K Hedna, K Heser, KU Saum, L Bertram, M Abu Sin, M Butler, M König, M König, M Molokhia, Maximilian König, ME Charlson, MH Beers, ML Laroche, MM Wolfe, MP Oktora, N Kachru, N Masnoon, O Abraham, O Reich, P Gallagher, P Gallo, P Martinot, PH Novaes, PJ McLeod, R Linder, Reinhold Kreutz, RT Chlebowski, RU Kristensen, S Holt, S Trelle, Sarah Toepfer, SK Nothelle, SM Wallerstedt, ST DeKosky, U Schwabe   +57 more
core   +1 more source

Extent and Incidence of Pseudo‐Worsening of Kidney Function Due to Oral Antitumor Therapeutics in the AMBORA Cohort: An Analysis of Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
A considerable number of oral antitumor therapeutics (OAT) has the potential for causing pseudo‐worsening of kidney function (PW) due to inhibition of renal creatinine secretion, i.e., kidney function is unaffected, while creatinine‐based calculation of glomerular filtration rate (eGFR) erroneously indicates an impaired kidney function.
Michael I. Sponfeldner, Pauline Dürr, Phyllis Lensker, Katja Gessner, Lisa Cuba, Rainer Fietkau, Markus F. Neurath, Bernd Wullich, Marianne Pavel, Carola Berking, Matthias W. Beckmann, Andreas Mackensen, Frank Dörje, Martin F. Fromm   +13 more
wiley   +1 more source