Results 1 to 10 of about 76,289 (330)
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes
Nature Communications, 2020 An important assessment prior to genome assembly and related analyses is genome profiling, where the k-mer frequencies within raw sequencing reads are analyzed to estimate major genome characteristics such as size, heterozygosity, and repetitiveness ...
T Rhyker Ranallo-Benavidez +2 more
exaly +2 more sources
Nature Genetics, 2019 High oil and protein content make tetraploid peanut a leading oil and food legume. Here we report a high-quality peanut genome sequence, comprising 2.54 Gb with 20 pseudomolecules and 83,709 protein-coding gene models.
Weijian Zhuang, Meng Yang
exaly +2 more sources
The transcriptional landscape of polyploid wheat
Science, 2018 Insights from the annotated wheat genome Wheat is one of the major sources of food for much of the world. However, because bread wheat's genome is a large hybrid mix of three separate subgenomes, it has been difficult to produce a high-quality reference ...
Ricardo Ramirez-Gonzalez +2 more
exaly +2 more sources
Proliferative polyploid cells give rise to tumors via ploidy reduction
Nature Communications, 2021 Polyploidy is a hallmark of cancer, and closely related to chromosomal instability involved in cancer progression. Importantly, polyploid cells also exist in some normal tissues.
Tomonori Matsumoto +2 more
exaly +2 more sources
Plant Biotechnology Journal, 2014 High-density single nucleotide polymorphism (SNP) genotyping arrays are a powerful tool for studying genomic patterns of diversity, inferring ancestral relationships between individuals in populations and studying marker–trait associations in mapping ...
Shichen Wang +2 more
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Nature Communications, 2020 Our understanding of polyploid genome evolution is constrained because we cannot know the exact founders of a particular polyploid. To differentiate between founder effects and post polyploidization evolution, we use a pan-genomic approach to study the ...
Sean P Gordon +2 more
exaly +2 more sources
The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes
Nature Communications, 2014 Polyploidization has provided much genetic variation for plant adaptive evolution, but the mechanisms by which the molecular evolution of polyploid genomes establishes genetic architecture underlying species differentiation are unclear.
Shengyi Liu, Yumei Liu, Chaobo Tong
exaly +2 more sources
Oncogene, 2017 Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to which stage of normal ...
Na Niu, I. Mercado-uribe, J. Liu
exaly +2 more sources
Uncovering hidden variation in polyploid wheat
Proceedings of the National Academy of Sciences of the United States of America, 2017 Tyson Howell +2 more
exaly +2 more sources
Polyploid giant cancer cells (PGCC): short-term return to multicellularity. [PDF]
Biol ResVinogradov AE, Anatskaya OV.
europepmc +3 more sources