Results 31 to 40 of about 54,552 (286)

Multiomics Reveals the Molecular Mechanism of Collagen Synthesis by Hydrolyzed Collagen Supplementation of Large Yellow Croaker (Larimichthys crocea)

Aquaculture Nutrition
This study investigated the effects of dietary hydrolyzed collagen supplementation on muscle quality and its underlying molecular mechanisms in large yellow croaker (Larimichthys crocea) (initial weight: 332.27 ± 3.79 g) over a 128-day feeding trial. The
Fangle Tong, Xuexue Zhang, Lina Zhang, Xiaocheng Deng, Yalan Zhang, Shi Wang, Zehong Wei   +6 more
doaj   +1 more source

Assessment of Germplasm Improvement in Three Farmed Grass Carp Populations Based on Genetic Variability

Biology
The assessment of genetic improvement was comprehensively analyzed using the mtDNA Cyt b gene and SSR markers among three farmed grass carp populations caught in May 2024.
Zhongyuan Shen, Liming Shao, Xixi Liu, Haiqi Li, Haipeng Guo, Lang Qin, Kaikun Luo, Wuhui Li, Jing Wang, Shengnan Li, Qianhong Gu, Liang Guo, Xu Huang, Qinbo Qin, Shaojun Liu   +14 more
doaj   +1 more source

Minimum error correction-based haplotype assembly: considerations for long read data

, 2020
The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome.
de Ridder, Dick, Kahaei, Mohammad Hossein, Majidian, Sina   +2 more
core   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Multi-omics interrogation of herbivorous phenotype acquisition in hybrid culter under a 30% crude protein diet

BMC Genomics
Background Herbivorous teleosts represent eco-efficient alternatives for sustainable aquaculture, yet the molecular drivers of herbivory in hybrid culter remain elusive.
Yuxiang Wang, Jinhui Huang, Ming Wen, Hongxuan Liang, Yingying Yang, Lang Qin, Le Shen, Jiawang Huang, Xu Huang, Zhuangwen Mao, Fangzhou Hu, Chang Wu, Shaojun Liu   +12 more
doaj   +1 more source

Evaluation of Hypoxia Tolerance and Cloning-Expression Analysis of Related Genes in Hybrid Fish Derived from Megalobrama amblycephala × Xenocypris davidi Bleeker

Fishes
The diploid distant hybrid (2nBY) derived from female blunt snout bream (Megalobrama amblycephal, BSB) × male Bleeker’s yellow tail (Xenocypris davidi Bleeker, YT).
Zhong Tang, Xinxin Yu, Xin Chen, Junwen Liang, Yangyang Tu, Zhifeng Zhou, Faxian Yu, Chun Zhang, Siyu Fan, Min Tao   +9 more
doaj   +1 more source

Biogeographic Population Structure of Chimeric Blades of Porphyra in the Northeast Atlantic Reveals Southern Rich Gene Pools, Introgression and Cryptic Plasticity

Frontiers in Plant Science, 2022
The genus Porphyra sensu lato (Bangiaceae, Rhodophyta), an important seaweed grown in aquaculture, is the most genetically diverse group of the Class Bangiophyceae, but has poorly understood genetic variability linked to complex evolutionary processes ...
Elena Varela-Álvarez, Patrick G. Meirmans, Michael D. Guiry, Ester A. Serrão   +3 more
doaj   +1 more source

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

Advanced Science, EarlyView.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang, Yaodong Gu, Wen Du, Lin Xie, Jinwei Quan, Yu Zhao, Ye Cheng, Zhaonan Wei, Yuanyuan Sha, Yi Wang, Dechao Xu, Xiang Gao, Min Chen, Xiangchen Gu   +13 more
wiley   +1 more source

Chromatin-mediated mechanisms of hybrid fertility in F1 male hybrids of Culter alburnus and Megalobrama amblycephala

BMC Biology
Background Interspecific hybridization is a fundamental evolutionary process, yet it often results in male sterility due to genomic incompatibilities and disrupted epigenetic regulation.
Li Ren, Kai Yang, Yiyan Zeng, Ruyi Zhang, Ling Liu, Huiya Guan, Jinhui Zhang, Xiaohuan Han, Shaojun Liu   +8 more
doaj   +1 more source

Evidence for Paternal Mitochondrial DNA Leakage in Diploid Hybrid Fish Lineages

Animals
Distant hybridization induces genomic instability in offspring, driving the occurrence of gene recombination and mutation. Analysis of the genomic genetic composition can be used to infer the genetic evolutionary relationships between species.
Yalan Zhang, Qinglin Xu, Wei Chen, Sijin Fan, Yu Hu, Xinyue Deng, Gaode Zhong, Kaikun Luo, Mingli Chai, Huan Zhong, Wuhui Li, Fangzhou Hu, Shi Wang, Shaojun Liu   +13 more
doaj   +1 more source