Results 111 to 120 of about 54,552 (286)

Harnessing Bulk‐Segregant Mapping to Identify Trait‐Associated Genes in the Allopolyploid Model Plant Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT Forward genetics has been instrumental in identifying genes underlying desirable traits, yet its application to polyploid plants, many of which are key agricultural crops, remains challenging due to their genomic complexity. Therefore, we developed BenthMap, a bulk segregant analysis platform for high‐throughput trait mapping and gene ...
Zuba Ahmed, Jiyuan An, Satomi Hayashi, Julia Bally, Chris Winefield, Peter M. Waterhouse   +5 more
wiley   +1 more source

Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner. [PDF]

, 2017
Glioblastoma is associated with a poor overall survival despite new treatment advances. Antiangiogenic strategies targeting VEGF based on tyrosine kinase inhibitors (TKIs) are currently undergoing extensive research for the treatment of glioma.
Amantini, C, BERNARDINI, Giovanni, CARDINALI, CLAUDIO, MORELLI, MARIA BEATRICE, Nabissi, M, SANTONI, Angela, Santoni, G., Santoni, M   +7 more
core   +1 more source

PlantCTCIP: Chromatin Interaction Prediction Using Convolutional Neural Network and Transformer in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Chromatin interactions establish spatial proximity between distant regulatory elements and their target genes, significantly influencing gene expression, and phenotypic traits. In this study, we present a plant chromatin interaction prediction model called PlantCTCIP based on Convolutional Neural Networks and Transformer.
Zhenye Wang, Siyu Zhou, Ze Guo, Zilan Ning, Jiaqi Cai, Ran Zhao, Ao Xie, Quan Li, Jiangling Zhang, Yongsheng Zhao, Peizhang Li, Haiping Si, Jianbing Yan, Yong Peng, Jianxiao Liu   +14 more
wiley   +1 more source

Identification of Three POMCa Genotypes in Largemouth Bass (Micropterus salmoides) and Their Differential Physiological Responses to Feed Domestication

Animals
Diverse feeding habits in teleosts involve a wide range of appetite-regulating factors. As an appetite-suppressing gene, the polymorphisms of POMCa in largemouth bass (Micropterus salmoides) were validated via sequencing and high-resolution melting (HRM).
Jie Hu, Jie Yang, Huan Zhong, Qifang Yu, Jun Xiao, Chun Zhang   +5 more
doaj   +1 more source

A Phylogenetic Analysis of the Genus Fragaria (Strawberry) Using Intron-Containing Sequence from the ADH-1 Gene [PDF]

, 2014
The genus Fragaria encompasses species at ploidy levels ranging from diploid to decaploid. The cultivated strawberry, Fragaria×ananassa, and its two immediate progenitors, F. chiloensis and F. virginiana, are octoploids.
Davis, Thomas M., DiMeglio, Laura M., Staudt, Gunter, Yu, Hongrun   +3 more
core   +1 more source

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, EarlyView.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

“Targeted Sequencing by Gene Synteny,” a New Strategy for Polyploid Species: Sequencing and Physical Structure of a Complex Sugarcane Region

Frontiers in Plant Science, 2018
Sugarcane exhibits a complex genome mainly due to its aneuploid nature and high ploidy level, and sequencing of its genome poses a great challenge. Closely related species with well-assembled and annotated genomes can be used to help assemble complex ...
Melina C. Mancini, Claudio B. Cardoso-Silva, Danilo A. Sforça, Anete Pereira de Souza, Anete Pereira de Souza   +4 more
doaj   +1 more source

Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis and Leaf Morphology

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sweet potato (Ipomoea batatas) exhibits diversity in pigmentation and leaf morphology, yet the genetic architecture and regulatory organisation underlying these traits remain poorly resolved, particularly with respect to organ‐specific control.
Dong An, Tiechen Shen, Shiyu Wu, Yanshen Li, Weijuan Fan, Mengxiao Yan, Yinghui Meng, Xinyi Wang, Ximing Xu, Zunfu Lv, Ling Yuan, Jun Yang, Guoquan Lu, Hongxia Wang   +13 more
wiley   +1 more source

Variation in nuclear genome size in a freshwater snail model system featuring a recent whole-genome duplication

Royal Society Open Science
Conspecifics often share—or are assumed to share—nuclear genome characteristics like nucleotide composition and genome size. These fundamental aspects of the nuclear genome can themselves be the object of natural selection. We here provide the first high-
Maurine Neiman, Maria Pichler, Martin Haase, Dunja K. Lamatsch   +3 more
doaj   +1 more source

Reassessment of the evolution of wheat chromosomes 4A, 5A, and 7B. [PDF]

, 2018
Key messageComparison of genome sequences of wild emmer wheat and Aegilops tauschii suggests a novel scenario of the evolution of rearranged wheat chromosomes 4A, 5A, and 7B.
Deal, Karin R, Devos, Katrien M, Distelfeld, Assaf, Dvorak, Jan, Gill, Bikram S, Gu, Yong Q, Jorgensen, Chad M, Luo, Ming-Cheng, McGuire, Patrick E, Qi, Peng, Wang, Le, Zhu, Tingting   +11 more
core