Results 81 to 90 of about 17,851 (240)

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

PanGraphRNA: An efficient and flexible bioinformatics platform for graph pangenome‐based RNA‐seq data analysis

Journal of Integrative Plant Biology, EarlyView.
PanGraphRNA is an easy‐to‐use platform that improves RNA‐seq analysis by using graph pangenomes instead of a single reference genome. It increases read alignment accuracy, detects important genes missed by traditional methods, and works across major crops, helping researchers obtain more reliable transcriptome results for diverse plant research and ...
Yifan Bu, Zhixu Qiu, Wen Sun, Yishui Han, Yifan Liu, Jing Yang, Minggui Song, Zenglin Li, Songyu Liu, Yuzhou Zhang, Chuang Ma   +10 more
wiley   +1 more source

A poly approach to ploidy : polyploid evolution and taxonomic implications

, 2011
Polyploidy, i.e., the duplication of entire nuclear genomes, has shaped the evolution of major lineages of eukaryotes, and is particularly important in the Plant Kingdom.
Jørgensen, Marte Holten
core   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

Intra- and Inter-Specific Crosses among Centaurea aspera L. (Asteraceae) Polyploid Relatives-Influences on Distribution and Polyploid Establishment [PDF]

, 2020
[EN] How polyploids become established is a long-debated question, especially for autopolyploids that seem to have no evolutionary advantage over their progenitors. The Centaurea aspera polyploid complex includes diploid C.
Ferrer-Gallego, P. Pablo, María Ferriol, Garmendia, Alfonso, David Benavent, Ferriol Molina, María, Merle Farinós, Hugo Basilio, Hugo Merle, Benavente, David, Alfonso Garmendia, P. Pablo Ferrer-Gallego   +9 more
core   +1 more source

High‐quality genome of elite peanut cultivar ZH05 reveals subgenome asymmetry, pan‐genome diversity, and breeding insights

Journal of Integrative Plant Biology, EarlyView.
A high‐quality reference genome for the elite peanut cultivar Zhonghua No. 5 revealed differing evolutionary paths between the two peanut subgenomes. SubA has higher overall gene expression and more open chromatin, whereas SubB has stronger structural organization, higher DNA methylation, and greater adaptive diversity associated with peanut evolution ...
Taihua Yang, Nian Liu, Li Huang, Jianbin Guo, Xiaomeng Xue, Mingjun Wang, Xiaohan Zhang, Chengtao Quan, Enyou Feng, Jiazhuang Tan, Zhenzhen Zhang, Yu You, Youlin Xia, Dongxin Huai, Yuning Chen, Liyin Yan, Kede Liu, Huifang Jiang, Yong Lei, Boshou Liao   +19 more
wiley   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high-throughput RNA sequencing. [PDF]

Plant Genome
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
Santoro DF, Carballo J, Pasten MC, Gallo CA, Albertini E, Echenique V.   +5 more
europepmc   +2 more sources

Sugarcane breeding array 1.0: A high‐density SNP chip for genomic studies and molecular breeding

Journal of Integrative Plant Biology, EarlyView.
Sugarcane Breeding Array 1.0, a high‐density single‐nucleotide polymorphism array, is based on deep whole‐genome resequencing of diverse sugarcane accessions. Validation demonstrated its robust performance and cost‐effectiveness in population structure analysis, genome‐wide association studies, and molecular breeding applications.
Meiyan Chen, Chaohua Xu, Ni Wei, Bowen Kuang, Peng Liu, Jinkang Song, Bo Yu, Fengzhen Wu, Xin Lu, Xiping Yang   +9 more
wiley   +1 more source

Unraveling the complex genome of Saccharum spontaneum using Polyploid Gene Assembler [PDF]

, 2019
The Polyploid Gene Assembler (PGA), developed and tested in this study, represents a new strategy to perform gene-space assembly from complex genomes using low coverage DNA sequencing.
Carvalho, Guilherme M A, Yanagui, Karina, Grassi, Maria Carolina B, Pereira, Gonçalo A G, Prado, Paula F, Carvalho, Carlos Roberto, Cunha, Camila P, Carazzolle, Marcelo F, Nascimento, Leandro Costa, Camargo, Eduardo L O, Bressiani, José Antonio, Mieczkowski, Piotr, Jose, Juliana   +12 more
core   +2 more sources

The multifaceted regulatory network of microRNA396: Orchestrating plant plasticity through coordinating development and various stresses

Journal of Integrative Plant Biology, EarlyView.
This review examines the character and function of the microRNA miR396, which helps plants balance growth, reproduction, regeneration, and survival under various stresses, highlighting recent progress and evidence that this pathway shapes crop yield, pest and disease resistance, and tissue regeneration, making it a promising target for precision crop ...
Hang Yang, Ying Yan, Lixia Zhang, Junhua Ye, Kai Wang, Zejun Hu, Lingjuan Xie, Liming Cao, Shujun Wu, Zhenying Shi   +9 more
wiley   +1 more source