Results 71 to 80 of about 12,812 (219)
Cell Biology International, Volume 50, Issue 6, June 2026.ABSTRACT Platelet shortages and limited storage stability restrict global platelet transfusion capacity, highlighting the need for efficient in vitro platelet production systems. This study establishes a simple, non‐genetic and cost‐effective system for efficient in vitro platelet‐like particle (PLP) production from human hematopoietic stem/progenitor ...
Nittaya Jiamvoraphong +8 more
wiley +1 more source
BMP2K dysregulation promotes abnormal megakaryopoiesis in acute megakaryoblastic leukemia
Cell & Bioscience, 2020 Background Forced polyploidization is an effective strategy for acute megakaryoblastic leukemia (AMKL) therapy and factors controlling polyploidization are potential targets for drug development. Although bone morphology protein 2-inducible kinase (BMP2K)
Manman Wang +5 more
doaj +1 more source
Outcomes of hypothetical alternate polyploidization pathways.
, 2023 An organism can become neopolyploid through multiple pathways representing a gradient of least likely to result in polyploid lineage establishment (an evolutionary dead end) to most to likely (the hypothetical optimal polyploidization pathway).
Kelley Leung (17328090) +2 more
core +1 more source
PlantsStevia rebaudiana (Bertoni) is a valuable sweetener plant whose sweetness primarily derives from steviol glycosides (SGs), especially rebaudioside A (RA). Polyploidization has the potential to enhance the content of active ingredients in medicinal plants,
Juan Liu +8 more
doaj +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, Volume 2, Issue 2, June 2026.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
Inter- and interspecific serological relationships in Pellia epiphylla complex
Acta Societatis Botanicorum Poloniae, 2014 Antigenic proteins were used as markers for the study of relationships between three liverwort species from P. epiphylla complex. It has recently been shown that the electrophoretic phenotypes of this species suggested an amphiploid origin of P. borealis.
Aleksandra Wojnicka-Półtorak +2 more
doaj +1 more source
New Zealand Journal of Botany, Volume 64, Issue 2, June 2026.Yakushima Island is a major biodiversity hotspot where complex environmental gradients and high endemism provide an ideal setting for studying plant evolution. In this study, we investigated the relationships among ploidy variation, morphology, and environmental factors in populations of Plagiogyria adnata, including the variety P.
Diego Tavares Vasques +4 more
wiley +1 more source
Hepatocyte polyploidization and its association with pathophysiological processes
, 2017 A characteristic cellular feature of the mammalian liver is the progressive polyploidization of the hepatocytes, where individual cells acquire more than two sets of chromosomes.
Fei Chen +3 more
core +1 more source
Production of compact petunias through polyploidization [PDF]
, 2017 Petunia, a commercially important ornamental plant worldwide, has been subjected to breeding programs that have yielded a high number of varieties. One of the key factors in the commercial value of these varieties is plant compactness. Currently, compact
Encina, C. L. +11 more
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Polyploidization and epigenetics [PDF]
Chinese Science Bulletin, 2011 The occurrence of polyploidy, or whole genome duplication, can result in instantaneous speciation. Because new polyploids are immediately reproductively isolated from their non-polyploid congeners, polyploidization has played an important role in the diversification of flowering plants and some vertebrates.
Li, ZhiHui +8 more
openaire +1 more source