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Polyploidy : methods and protocols
This volume provides protocols on evidence for polyploidy and how it can be unveiled. Chapters guide readers through evolutionary experiments, measure effects of polyploidy, evidence for (remnants of) ancient WGDs, models of chromosome number evolution ...
Van de Peer, Yves
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Polyploidy (whole-genome duplication) has played a pervasive role in the evolution of fungi and animals, and is particularly prominent in plants (Wendel & Doyle, 2005; Cui et al., 2006; Otto, 2007; Wood et al., 2009).
Ainouche, Malika +2 more
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Polyploidy in Bryum collected from the Syowa Station area, Antarctica
Bryum pseudotriquetrum (HEDW.) GAERTN., MEYER et SCHERB. and B. amblyodon C. MUELL. collected from the Syowa Station area, Antarctica are karyologically studied with particular regard to the polyploidy.
Hiroshi Kanda, Hiroshi Okada
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Polyploidy Index and Its Implications for the Evolution of Polyploids
Polyploidy has contributed to the divergence and domestication of plants; however, estimation of the relative roles that different types of polyploidy have played during evolution has been difficult.
Jinpeng Wang +43 more
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Polyploidy is defined as an increase in genome DNA content. Throughout the plant and animal kingdoms specific cell types become polyploid as part of their differentiation programs. When this occurs in subsets of tissues within an organism it is termed somatic polyploidy, because it is distinct from the increase in ploidy that is inherited through the ...
Frawley, Laura E., Orr-Weaver, Terry L.
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Ploidy-Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells. [PDF]
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Haim-Abadi G, Benvenisty N.
europepmc +2 more sources
Polyploidy and the proteome [PDF]
Although major advances have been made during the past 20 years in our understanding of the genetic and genomic consequences of polyploidy, our knowledge of polyploidy and the proteome is in its infancy. One of our goals is to stimulate additional study, particularly broad-scale proteomic analyses of polyploids and their progenitors. Although it may be
Douglas E, Soltis +4 more
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Cellular polyploidy in organ homeostasis and regeneration [PDF]
Polyploid cells, which contain more than one set of chromosome pairs, are very common in nature. Polyploidy can provide cells with several potential benefits over their diploid counterparts, including an increase in cell size, contributing to organ ...
Schiffelers, Raymond +12 more
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Chromosomal aberrations in transitional cell carcinoma that are predictive of disease outcome are independent of polyploidy [PDF]
Objective To determine whether aneusomy for chromosomes 7, 9 and 17 (reported to predict recurrence in up to 65% of patients with superficial transitional cell bladder cancer and thus providing the opportunity for early and effective treatment) reflects ...
Watters, A.D. +4 more
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This review summarizes the current status of the known extant genuine polyploid anuran and urodelan species, as well as spontaneously originated and/or experimentally produced amphibian polyploids. The mechanisms by which polyploids can originate, the meiotic pairing configurations, the diploidization processes operating in polyploid genomes, the ...
Schmid, Michael +2 more
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