Results 41 to 50 of about 30,417 (268)

Polyploidy in the Apple Polyploidy in the Apple

Journal of the American Pomological Society, 1952
In April 1942 six one-year-old apple trees of the varieties Baldwin, Delicious, McIntosh, Stayman and Winesap, were treated with colchicine. The technique used was essentially the same as that recommended for the pear 4. Although polyploidy was detected inn limited areas on some leaves during the first growing period following treatment, no branches ...
openaire   +1 more source

Production of autotetraploid plants by in vitro chromosome engineering in Allium hirtifolium

Horticultural Plant Journal, 2023
Persian shallot has been propagated vegetatively through daughter bulbs and has a narrow genetic base. In the present study, to create genetic diversity in terms of ploidy level, the effects of in vitro polyploidization were investigated on morphological,
Nasrin Farhadi, Jaber Panahandeh, Alireza Motallebi-Azar, Sam Mokhtarzadeh   +3 more
doaj   +1 more source

Tapak Liman (Elephantopus scaber) crude extract induces polyploidy in shallot root (Allium cepa war ascalonium (L)) [PDF]

E3S Web of Conferences
This study investigates the impact of induction time and concentration of Tapak Liman (Elephantopus scaber) crude extract on the effectiveness of polyploidy in shallot root (Allium cepa var ascalonium (L).
Isnawati, Muhaimin Fitriari Izzatunnisa, Fudhaili Ahmad   +2 more
doaj   +1 more source

Integration of the D‐Genome Reshapes Gene Transcription, Chromatin Architecture, and Metabolome of Allohexaploid Wheat, Leading to Enhanced Environmental Adaptability

Advanced Science, EarlyView.
Integration of the D‐genome reshapes gene transcription, chromatin architecture, and the metabolome of hexaploid wheat, leading to enhanced adaptability to salt, UV‐B, and alkali stress. ABSTRACT The hybridization‐led integration of the D‐genome into domesticated tetraploid wheat gave rise to allohexaploid wheat, the most cultivated wheat globally ...
Yanyan Liu, Tao Zhu, Ziru Zhou, Wei Chen, Chao He, Xinkai Zhou, Xin Wang, Chuanye Chen, Bo Yang, Jiaqi Wei, Caixia Lan, Mengmeng Liu, Handong Su, Qiang Li, Xin Hu, Siteng Bi, Weizhi Ouyang, Xingwang Li, Hailiang Mao, Masahiro Kishi, Kerstin Kaufmann, Alisdair R. Fernie, Dijun Chen, Wenhao Yan   +23 more
wiley   +1 more source

Aurkin-A, a TPX2-Aurora A small molecule inhibitor disrupts Alisertib-induced polyploidy in aggressive diffuse large B cell lymphoma

Neoplasia: An International Journal for Oncology Research
Chemotherapy induced polyploidy is a mechanism of inherited drug resistance resulting in an aggressive disease course in cancer patients. Alisertib, an Aurora Kinase A (AK-A) ATP site inhibitor, induces cell cycle disruption resulting in polyaneuploidy ...
Patrick J. Conway, Bárbara De La Peña Avalos, Jonathan Dao, Sebastian Montagnino, Dmytro Kovalskyy, Eloise Dray, Daruka Mahadevan   +6 more
doaj   +1 more source

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula, Juvy Rabelas, Kareem Touleimat, Elaine Marchi, Ruhi Shah, Shaydah Kheradmand, Kuldeep Singh, Karen Amble, Gholson J. Lyon   +8 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Polyploidy in liver development, homeostasis and disease

, 2020
International audiencePolyploidy (or whole-genome duplication) is the condition of having more than two basic sets of chromosomes. Polyploidization is well tolerated in many species and can lead to specific biological functions.
Celton-Morizur, Séverine, Desdouets, Chantal, Pierre Cordier, Romain Donne, Donne, Romain, Saroul-Aïnama, Maëva, Cordier, Pierre, Maëva Saroul-Aïnama, Séverine Celton-Morizur, Chantal Desdouets   +9 more
core   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Capillary Endothelia from Two ADPKD Patients are Polyploidy [PDF]

, 2016
Bilateral renal cyst formation is the main feature of autosomal dominant polycystic kidney disease (ADPKD). We and other laboratories have previously shown that cystlining epithelia of kidneys from ADPKD patients are characterized by polyploidy.
AbouAlaiwi, Wissam A., Zi, Xiaolin, Nauli, Surya M., Kathem, Sarmed H.   +3 more
core   +1 more source