Results 41 to 50 of about 27,168 (249)
Neoplasia: An International Journal for Oncology ResearchChemotherapy induced polyploidy is a mechanism of inherited drug resistance resulting in an aggressive disease course in cancer patients. Alisertib, an Aurora Kinase A (AK-A) ATP site inhibitor, induces cell cycle disruption resulting in polyaneuploidy ...
Patrick J. Conway +6 more
doaj +1 more source
Regulated polyploidy in halophilic archaea
, 2006 Polyploidy is common in higher eukaryotes, especially in plants, but it is generally assumed that most prokaryotes contain a single copy of a circular chromosome and are therefore monoploid.
Jörg Soppa +7 more
core +1 more source
Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
Advanced Science, EarlyView.PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source
Horticulturae, 2021 Limonium sinuatum (L.) Mill. (2n = 2x = 16) is a popular ornamental plant with dimorphism of pollen grains (type A and type B) and stigmas (papilla and cob-like).
Shiro Mori +10 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Polyploidy in the Apple Polyploidy in the Apple
Journal of the American Pomological Society, 1952 In April 1942 six one-year-old apple trees of the varieties Baldwin, Delicious, McIntosh, Stayman and Winesap, were treated with colchicine. The technique used was essentially the same as that recommended for the pear 4. Although polyploidy was detected inn limited areas on some leaves during the first growing period following treatment, no branches ...
openaire +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin +7 more
wiley +1 more source
Diagnostic Cytopathology, EarlyView.ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley +1 more source
The Impact of Age and Carbon Tetrachloride on Hepatic Polyploidy in Albino Rats (A Histological and Immunohistological Study) [PDF]
Al-Azhar International Medical JournalBackground: Polyploidy, a condition where cells contain more than two sets of homologous chromosomes, is a unique feature of hepatocytes. However, its biological significance remains incompletely understood.
Ahmed Al-Shenawy +3 more
doaj +1 more source
Frontiers in Plant Science, 2022 Artificial polyploidy that brings about increase in cell size confers changes in histo-morphology leading to altered phenotype, causing changes in physiological attributes and enhanced concentration of secondary metabolites.
Yerramilli Vimala +5 more
doaj +1 more source