Results 91 to 100 of about 1,138,603 (357)

Clinical management of endoscopically resected pT1 colorectal cancer [PDF]

, 2018
Background Implementation of colorectal cancer (CRC) screening programs increases endoscopic resection of polyps with early invasive CRC (pT1). Risk of lymph node metastasis often leads to additional surgery, but despite guidelines, correct management ...
Angeletti, Stefano, Antonelli, Giulio, Berardi, Giammauro, Brescia, Antonio, Corleto, Vito Domenico, D'Ambra, Giancarlo, Di Giulio, Emilio, Hassan, Cesare, Mercantini, Paolo, Pilozzi, Emanuela, Rampioni Vinciguerra, Gian Luca, Ruggeri, Maurizio   +11 more
core   +1 more source

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman, Carli M. Tops, Jelmer Legebeke, Ting Yang, Marcos Díaz Gay, Diantha Terlouw, Lisa E. E. L. O. Lashley, Stefan Aretz, Anna K. Sommer, Mariona Terradas, Laura Valle, Richarda M. de Voer, Ludmil B. Alexandrov, Hans Morreau, Tom van Wezel, Maartje Nielsen   +15 more
wiley   +1 more source

Effect and Threshold of Endoscopic Findings for CRS Control Status and Long‐Term Outcome Prediction

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background EPOS 2020 defined chronic rhinosinusitis (CRS) disease control using patient symptoms and medication usage but endoscopic findings were considered optional. The effect of adding endoscopic features, an appropriate threshold, and their association with present or future symptom control have not been studied.
Steven Chun‐Kang Liao, Aditi Agarwal, Junqin Bai, Zhidi Luo, Siyuan Dong, Regan L. Harmon, Brooke N. Gleason, Julia Huang, David B. Conley, Kevin C. Welch, Stephanie Shintani‐Smith, Robert C. Kern, Atsushi Kato, Lutfiyya N. Muhammad, Bruce K. Tan   +14 more
wiley   +1 more source

Negative Predictors of Tooth Extraction in the Management of Odontogenic Sinusitis in a Japanese Patient Population: A Retrospective Study

International Archives of Otorhinolaryngology
Introduction There are no clear guidelines for deciding between endoscopic sinus surgery and tooth extraction for the treatment of odontogenic sinusitis.
Kazuhiro Hirasawa, Koji Otsuka, Renako Tomaru, Naoki Ikehata, Kiyoaki Tsukahara   +4 more
doaj   +1 more source

Managing chronic rhinosinusitis in adults [PDF]

, 2016
Commentary by Carl Philpott, Clinical Senior Lecturer, Norwich Medical School and Honorary Consultant Ear, Nose and Throat Surgeon and Rhinologist, James Paget University Hospital: “The evidence presented by Rudmik et al.
Philpott, Carl
core  

An Efficient Approach for Polyps Detection in Endoscopic Videos Based on Faster R-CNN

, 2018
Polyp has long been considered as one of the major etiologies to colorectal cancer which is a fatal disease around the world, thus early detection and recognition of polyps plays a crucial role in clinical routines.
Mo, Xi, Tao, Ke, Wang, Guanghui, Wang, Quan   +3 more
core   +1 more source

Early and Sustained Improvements in Sense of Smell With Tezepelumab Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyps (WAYPOINT)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Loss of smell is a principal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), affecting health‐related quality of life and posing a safety hazard. Methods WAYPOINT (NCT04851964), a phase 3, multicenter trial in adults with uncontrolled CRSwNP, randomized patients 1:1 to receive tezepelumab 210 mg or placebo ...
Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose   +14 more
wiley   +1 more source

Fast Object Detection Leveraging Global Feature Fusion in Boundary-Aware Convolutional Networks

Information
Endoscopy, a pervasive instrument for the diagnosis and treatment of hollow anatomical structures, conventionally necessitates the arduous manual scrutiny of seasoned medical experts. Nevertheless, the recent strides in deep learning technologies proffer
Weiming Fan, Jiahui Yu, Zhaojie Ju
doaj   +1 more source

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park, Brooke N. Gleason, Eli Stein, Saied Ghadersohi, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan   +9 more
wiley   +1 more source

Simple sugars in fruit and the presence of colorectal cancers and polyps

Journal of Education, Health and Sport, 2017
The current knowledge based on facts provides data regarding genetic and environmental factors relevant for malignancies, including colorectal cancer (CRC) which frequently occurs in well-developed countries.
Piotr Sikorski, Małgorzata Szamocka, Agnieszka Meder, Monika Anna Ameryk, Maciej Świątkowski   +4 more
doaj