Results 41 to 50 of about 987,640 (269)

Polyp-SAM: transfer SAM for polyp segmentation

Medical Imaging 2024: Computer-Aided Diagnosis
Colon polyps are considered important precursors for colorectal cancer. Automatic segmentation of colon polyps can significantly reduce the misdiagnosis of colon cancer and improve physician annotation efficiency. While many methods have been proposed for polyp segmentation, training large-scale segmentation networks with limited colonoscopy data ...
Yuheng Li, Mingzhe Hu, Xiaofeng Yang
openaire   +2 more sources

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Cloacogenic polyp: a rare type of polyp [PDF]

Endoscopy, 2021
Thomas, Lambin, Pierre-Marie, Lavrut, Pierre, Lafeuille, Jérôme, Rivory, Florian, Rostain, Paul, Bonniaud, Mathieu, Pioche   +6 more
openaire   +2 more sources

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

Advanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu, Haitao Gao, Qingyang Liu, Sishen Yuan, Haiyang Fang, Mingwu Su, Baijia Liang, Yongzun Yang, Long Bai, Wenzhen Dong, Dihong Xie, Shijian Su, Jiewen Lai, Shing Shin Cheng, Zhen Li, Xiuli Zuo, Hongliang Ren   +16 more
wiley   +1 more source

Inflammatory mediators in nasal secretion in patients with bronchial asthma and allergic rhinitis with or without polyposis and hypertrophic sinonasal mucosa [PDF]

Exploration of Medicine
Aim: The pathogenetic mechanisms and predictors of the development of polyposis and hypertrophy of the sinonasal mucosa (SM) in patients with chronic allergic airway inflammation have not been clearly established.
Svetlana Viktorovna Krasilnikova, Ekaterina Ivanovna Krestova, Tatyana Ivanovna Eliseeva, Regina Niyazovna Khramova, Ksenia Viktorovna Gorbunova, Elena Alekseevna Leontieva, Dmitry Yuryevich Ovsyannikov, Natalia Anatolievna Geppe, Nailya Iskhakovna Kubysheva   +8 more
doaj   +1 more source

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, EarlyView.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

Polyp Genetics [PDF]

Clinics in Colon and Rectal Surgery, 2016
AbstractThe genetic events involved in the transformation of normal colonic epithelium to neoplastic polyps to invasive carcinoma, as initially proposed by Fearon and Vogelstein, form the foundation of our understanding of colorectal cancer. The identification of the polyp as the precursor lesion to colorectal cancer is the basis of many of our current
Coen Laurens, Klos, Sekhar, Dharmarajan
openaire   +2 more sources

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large‐Scale Retrospective Cohort Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are two highly prevalent airway diseases in the United States. While the coexistence of CRS and asthma is well recognized, less is known about the development of new‐onset asthma in CRS, particularly in the context of comorbid AR. This study assessed the impact of CRS and AR on
Austin J. Lee, Mohamad R. Chaaban
wiley   +1 more source

Reducing Fungal Exposure Critical for Treating Rhinosinusitis with or without Polyps [Letter]

Journal of Asthma and Allergy, 2021
Luke Curtis Eastern Carolina University, Greenville, NC, USACorrespondence: Luke CurtisEastern Carolina University, Greenville, NC, USATel +1 847-769-4768Email LukeCurtis1328@gmail.com I read with great interest your recent fascinating 2021 review by ...
Curtis L
doaj