The Origin of the RNA World: a Kinetic Model [PDF]
The aims of this paper are to propose, construct and analyse microscopic kinetic models for the emergence of long chains of RNA from monomeric beta-D-ribonucleotide precursors in prebiotic circumstances. Our theory starts out from similar but more general chemical assumptions to those of Eigen, namely that catalytic replication can lead to a large ...
arxiv
Comparative analyses of proteins from Haemophilus influenzae biofilm and planktonic populations using metabolic labeling and mass spectrometry [PDF]
BACKGROUND: Non-typeable H. influenzae (NTHi) is a nasopharyngeal commensal that can become an opportunistic pathogen causing infections such as otitis media, pneumonia, and bronchitis. NTHi is known to form biofilms.
Apicella, Michael A+6 more
core +2 more sources
Functional Genomic Analysis of Human Mitochondrial RNA Processing [PDF]
SummaryBoth strands of human mtDNA are transcribed in continuous, multigenic units that are cleaved into the mature rRNAs, tRNAs, and mRNAs required for respiratory chain biogenesis.
Mootha, Vamsi K., Wolf, Ashley R.
core +2 more sources
Toxicoproteomic evaluation of carbon nanomaterials in vitro [PDF]
Carbon nanotubes (CNTs) have already been successfully implemented in various fields, and they are anticipated to have innovative applications in medical science.
Aoki, Kaoru+12 more
core +1 more source
Localisation and interactions of the Vipp1 protein in cyanobacteria [PDF]
Biotechnology and Biological Sciences Research Council. Grant Number: BB/G021856. Deutsche Forschungsgemeinschaft. Grant Number: FOR 929, SCHN 690/3-1. European Commission. Grant Number: FP7-PEOPLE-2009-IEF 254575. NFR.
Bryan, SJ+13 more
core +5 more sources
On the origins of oxygenic photosynthesis and aerobic respiration in Cyanobacteria [PDF]
The origin of oxygenic photosynthesis in Cyanobacteria led to the rise of oxygen on Earth ~2.3 billion years ago, profoundly altering the course of evolution by facilitating the development of aerobic respiration and complex multicellular life.
Fischer, Woodward W.+4 more
core
Netemplátové aktivity DNA/RNA polymeráz a jejich význam [PDF]
Non-templated addition of adenosine on the 3' end of the product of several DNA polymerases commonly used in molecular biology has been a problematic yet unexplained phenomenon for a few decades now.
Pokorná, Kristýna
core
Proteomic Analysis Of Heat And Cold Stress Response Of Rhodobacter Capsulatus And Evolutionary Engineering Of Its Heat Resistant Mutants [PDF]
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2011Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2011Hidrojen biyolojik olarak üretilebilen gelecek vadeden alternatif bir enerji ...
Gökçe, Abdulmecit
core
Immunoproteomic analysis of bacterial proteins of Actinobacillus pleuropneumoniae serotype 1 [PDF]
Background Actinobacillus pleuropneumoniae (APP) is one of the most important swine pathogens worldwide. Identification and characterization of novel antigenic APP vaccine candidates are underway.
Liu, Guangjin+9 more
core +3 more sources
Efficient detection of RNA–protein interactions using tethered RNAs [PDF]
The diverse localization of transcripts in cells suggests that there are many specific RNA–protein interactions that have yet to be identified. Progress has been limited, however, by the lack of a robust method to detect and isolate the RNA-binding ...
Agris+15 more
core +2 more sources