Results 81 to 90 of about 3,855 (167)

The effect of permethrin cream on staphylococcal infections and studies on methicillin sensitive and resistant strains of Staphylococcus aureus [PDF]

, 2020
Antibiotic resistant strains of bacteria are a serious threat to human health. With increasing antibiotic resistance in common human pathogens, fewer antibiotics remain effective.
Nikolic, Philip
core  

A sequential co-extraction method for DNA, RNA and protein recovery from soil for future system-based approaches [PDF]

, 2014
A co-extraction protocol that sequentially isolates core biopolymer fractions (DNA, RNA, protein) from edaphic microbial communities is presented. In order to confirm compatibility with downstream analyses, bacterial T-RFLP profiles were generated from
Cowan, Don A., Frossard, Aline, Gunnigle, Eoin, Ramond, Jean-Baptiste, Seely, Mary   +4 more
core   +1 more source

Self-Resistance during Muraymycin Biosynthesis: a Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order

Antimicrobial Agents and Chemotherapy, 2018
Muraymycins are antibacterial natural products from Streptomyces spp. that inhibit translocase I (MraY), which is involved in cell wall biosynthesis. Structurally, muraymycins consist of a 5′-C-glycyluridine (GlyU) appended to a 5″-amino-5″-deoxyribose ...
Z. Cui, Xiachang Wang, Xiaodong Liu, Anke Lemke, Stefan Koppermann, C. Ducho, J. Rohr, J. Thorson, S. V. Van Lanen   +8 more
semanticscholar   +1 more source

Investigating the Development of Alcohol Tolerance in the ESKAPE Pathogens [PDF]

Antiseptics and disinfectants are used globally to kill or inhibit the growth of bacteria to prevent infection. Considering the well-documented development of antibiotic resistance, the potential for evolved tolerance to alcohol-based antimicrobial ...
Durkee, Hannah
core   +1 more source

A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control [PDF]

, 2005
Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors.
Amarasinghe, Anderson, Aravind, Arno Friedlein, Bard, Basavappa, Castaño, Cheng, Christofori, Crittenden, Dannull, de la Cruz, Diana Blank, Dichtl, Dichtl, Dirheimer, Dirheimer, Dreyfus, Edmonds, Falquet, Fountoulakis, Fromont-Racine, Georges Martin, Gerber, Gérard Keith, Hanno Langen, Holm, Inoue, Jeannette Wolf, Kadaba, Keith, Keller, Kuai, Kushner, Kwak, Li, Lingner, Martin, Martin, Martin, Martin, Minvielle-Sebastia, Mitchell, Mitchell, O'Hara, Ohnacker, Parker, Phillip Zamore, Preker, Proudfoot, Puig, Rain, Read, Sabine Dettwiler, Sadoff, Saitoh, Senger, Symmons, Torchet, van Hoof, Vijayraghavan, Wahle, Walowsky, Walter Keller, Wang, Wang, Wang, Wang, Wilm, Zhao, Zorio, Štěpánka Vaňáčová   +71 more
core   +5 more sources

Pnpt1 mediates NLRP3 inflammasome activation by MAVS and metabolic reprogramming in macrophages

bioRxiv, 2022
C. Hsu, Wenjia Li, M. Sowden, Camila Lage Chávez, B. Berk   +4 more
semanticscholar   +1 more source

Theoretical Studies on Mechanism of Inactivation of Kanamycin A by 4′-O-Nucleotidyltransferase

Frontiers in Chemistry, 2019
This work is focused on mechanistic studies of the transfer of an adenylyl group (Adenoside-5′-monophosfate) from adenosine 5′-triphosphate (ATP) to a OH-4′ hydroxyl group of an antibiotic.
S. Martí, Á. Bastida, K. Świderek
semanticscholar   +1 more source

Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins

Nature Communications
Nucleotidyltransferases (NTases) control diverse physiological processes, including RNA modification, DNA replication and repair, and antibiotic resistance.
Tom J Arrowsmith, Xibing Xu, Shangze Xu, B. Usher, Peter Stokes, Megan Guest, Agnieszka K. Bronowska, P. Genevaux, T. R. Blower   +8 more
semanticscholar   +1 more source

Depletion of tRNA CCA-adding enzyme in Mycobacterium tuberculosis leads to polyadenylation of transcripts and precursor tRNAs. [PDF]

Sci Rep, 2023
Błaszczyk E, Płociński P, Lechowicz E, Brzostek A, Dziadek B, Korycka-Machała M, Słomka M, Dziadek J.   +7 more
europepmc   +1 more source

Phenotypic Characterization of PNPase Mutation and Overexpression in C. elegans [PDF]

, 2019
PNPase, polynucleotide phosphorylase, is a multifunctional exoribonuclease protein with 3` terminal oligonucleotide polymerase activity. Coded by the PNPT1 gene, the protein is associated with mitochondrial homeostasis and functions as a possible target ...
Hur, Brian J
core   +1 more source