Results 51 to 60 of about 262,571 (196)

Characterization of a Novel PolyM-Preferred Alginate Lyase from Marine Vibrio splendidus OU02

Marine Drugs, 2018
Alginate lyases are enzymes that degrade alginate into oligosaccharides which possess a variety of biological activities. Discovering and characterizing novel alginate lyases has great significance for industrial and medical applications.
Jingjing Zhuang, Keke Zhang, Xiaohua Liu, Weizhi Liu, Qianqian Lyu, Aiguo Ji   +5 more
doaj   +1 more source

Capturing single cell genomes of active polysaccharide degraders: an unexpected contribution of Verrucomicrobia. [PDF]

PLoS ONE, 2012
Microbial hydrolysis of polysaccharides is critical to ecosystem functioning and is of great interest in diverse biotechnological applications, such as biofuel production and bioremediation.
Manuel Martinez-Garcia, David M Brazel, Brandon K Swan, Carol Arnosti, Patrick S G Chain, Krista G Reitenga, Gary Xie, Nicole J Poulton, Monica Lluesma Gomez, Dashiell E D Masland, Brian Thompson, Wendy K Bellows, Kai Ziervogel, Chien-Chi Lo, Sanaa Ahmed, Cheryl D Gleasner, Chris J Detter, Ramunas Stepanauskas   +17 more
doaj   +1 more source

Alginate degrading enzymes: an updated comprehensive review of the structure, catalytic mechanism, modification method and applications of alginate lyases

Critical Reviews in Biotechnology, 2021
Alginate, a kind of linear acidic polysaccharide, consists of α-L-guluronate (G) and β-D-mannuronate (M). Both alginate and its degradation products (alginate oligosaccharides) possess abundant biological activities such as antioxidant activity ...
Qian Li, Ling Zheng, Zilong Guo, Tiancheng Tang, Benwei Zhu   +4 more
semanticscholar   +1 more source

Characterization of Multiple Alginate Lyases in a Highly Efficient Alginate-Degrading Vibrio Strain and Its Degradation Strategy

Applied and Environmental Microbiology, 2022
Alginate is an important carbon source in the marine environment, and vibrios are major alginate utilizers. Previous studies focused only on the characteristics of individual alginate lyases in vibrios, but few of them discussed the comprehensive ...
Xinxin He, Yunhui Zhang, Xiaolei Wang, Xiaoyu Zhu, Lei-lei Chen, Weizhi Liu, Qianqian Lyu, Lingman Ran, Haojin Cheng, Xiaohua Zhang   +9 more
semanticscholar   +1 more source

Crystal Structure of Family 14 Polysaccharide Lyase with pH-dependent Modes of Action [PDF]

Journal of Biological Chemistry, 2009
The Chlorella virus enzyme vAL-1 (38 kDa), a member of polysaccharide lyase family 14, degrades the Chlorella cell wall by cleaving the glycoside bond of the glucuronate residue (GlcA) through a beta-elimination reaction. The enzyme consists of an N-terminal cell wall-attaching domain (11 kDa) and a C-terminal catalytic module (27 kDa).
Kohei, Ogura, Masayuki, Yamasaki, Takashi, Yamada, Bunzo, Mikami, Wataru, Hashimoto, Kousaku, Murata   +5 more
openaire   +2 more sources

Adaptations of Alteromonas sp. 76-1 to Polysaccharide Degradation: A CAZyme Plasmid for Ulvan Degradation and Two Alginolytic Systems

Frontiers in Microbiology, 2019
Studying the physiology and genomics of cultured hydrolytic bacteria is a valuable approach to decipher the biogeochemical cycling of marine polysaccharides, major nutrients derived from phytoplankton and macroalgae.
Hanna Koch, Heike M. Freese, Richard L. Hahnke, Meinhard Simon, Matthias Wietz   +4 more
doaj   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

A Novel Bifunctional Endolytic Alginate Lyase with Variable Alginate-Degrading Modes and Versatile Monosaccharide-Producing Properties

Frontiers in Microbiology, 2018
Endo-type alginate lyases usually degrade alginate completely into various size-defined unsaturated oligosaccharide products (≥disaccharides), while exoenzymes primarily produce monosaccharide products including saturated mannuronate (M) and guluronate ...
Chune Peng, Qingbin Wang, Danrong Lu, Wenjun Han, Fuchuan Li   +4 more
doaj   +1 more source

CAZymes in Maribacter dokdonensis 62–1 From the Patagonian Shelf: Genomics and Physiology Compared to Related Flavobacteria and a Co-occurring Alteromonas Strain

Frontiers in Microbiology, 2021
Carbohydrate-active enzymes (CAZymes) are an important feature of bacteria in productive marine systems such as continental shelves, where phytoplankton and macroalgae produce diverse polysaccharides.
Laura A. Wolter, Laura A. Wolter, Maximilian Mitulla, Jovan Kalem, Rolf Daniel, Meinhard Simon, Matthias Wietz, Matthias Wietz   +7 more
doaj   +1 more source

Alginate-modifying enzymes: Biological roles and biotechnological uses

Frontiers in Microbiology, 2015
Alginate denotes a group of industrially important 1-4-linked biopolymers composed of the C-5-epimers β-D-mannuronic acid (M) and α-L-guluronic acid (G).
Helga eErtesvåg
doaj   +1 more source