This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang+11 more
wiley +1 more source
Physicochemical Properties and Biological Activities of Polysaccharides from <i>Dendrobium officinale</i> Leaves in Response to Different Extraction Methods. [PDF]
Chen Y+5 more
europepmc +1 more source
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long+17 more
wiley +1 more source
Purification, Structural Characterization, Antioxidant Activity, and <i>In Vitro</i> Digestibility of Peach Gum Polysaccharide Extracted Using an Enzymatic Method. [PDF]
Cheng X, Chen S, Liu Y, Yang F, Chen J.
europepmc +1 more source
DETERMINATION OF POLYSACCHARIDE IN SERUM
Florence B. Seibert, Jane Atno
openalex +1 more source
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei+11 more
wiley +1 more source
Evaluation of a Multiplex Electrochemiluminescence Assay for Detection of Anti-Pneumococcal Antibodies in the Diagnosis of Selective Polysaccharide Antibody Deficiency. [PDF]
Perrard N+11 more
europepmc +1 more source
Pectin Metabolism Influences Phloem Architecture and Flowering Time in Arabidopsis Thaliana
Cell wall remodeling mediated by changes in pectic homogalacturonan, including its methyl‐esterification status and degradation, shapes wall architecture. This study finds that pectin metabolism dynamically modulates wall properties and triggers auxin responses, which influence phloem morphogenesis and function, mediating the long‐distance transport of
Qing Zhang+9 more
wiley +1 more source
Comparison of <i>Polygonatum sibiricum</i> Polysaccharides from Different Extraction Methods. [PDF]
Chen Y+10 more
europepmc +1 more source
The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong+27 more
wiley +1 more source