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Campylobacter polysaccharide capsules: virulence and vaccines [PDF]
Campylobacter jejuni remains a major cause of bacterial diarrhea worldwide and is associated with numerous sequelae, including Guillain Barre Syndrome, inflammatory bowel disease, reactive arthritis, and irritable bowel syndrome. C.
Patricia eGuerry+5 more
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Streptococcus pneumoniae is a major cause of community-acquired pneumonia, bacteremia, and meningitis in older adults worldwide. Two pneumococcal vaccines containing S.
Leela R. L. Davies+10 more
semanticscholar +1 more source
A Note on the Assay of Antigenic Polysaccharides and Vaccines [PDF]
Summary A method is described for the evaluation of antigenic pneumococcal polysaccharides and vaccines, based on a test commonly used to determine the number of LD50 doses neutralized. Protection was afforded mice by small amounts of SI not previously found protectively antigenic, when mice were infected three days after immunization ...
K. A. Ludwig+2 more
openalex +3 more sources
Streptococcus pneumoniae infection is the most common cause of high morbidity and mortality among children under 5 years of age, immunocompromised people, and the elderly.
M. V. Savkina+6 more
doaj +1 more source
Vaccination is a key component of public health policy with demonstrated cost-effective benefits in protecting both human and animal populations. Vaccines can be manufactured under multiple forms including, inactivated (killed), toxoid, live attenuated ...
Majed Ghattas+3 more
doaj +1 more source
A Vaccine Against Group B Streptococcus: Recent Advances [PDF]
Group B streptococcus (GBS) causes a high burden of neonatal and infant disease globally. Implementing a vaccine for pregnant women is a promising strategy to prevent neonatal and infant GBS disease and has been identified as a priority by the World ...
Carreras-Abad, C+3 more
core +2 more sources
Promising pharmaceutical development of vaccines for the prevention of meningococcal infection
Meningococcal infection (MI) refers to anthroponoses; is an acute infectious disease with an aerosol transmission mechanism, characterized by various forms of the infectious process: from local (nasopharyngitis) and asymptomatic infections to generalized
Maria V. Savkina+3 more
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Strengths and weaknesses of pneumococcal conjugate vaccines
Multivalent vaccines addressing an increasing number of Streptococcus pneumoniae types (7-, 10-, 13-, 15-, 20-valent) have been licensed over the last 22 years.
F. Micoli+4 more
semanticscholar +1 more source
Promising directions for vaccine development to prevent shigellosis
Shigellosis (bacterial dysentery) is an acute infectious disease caused by Shigella spp., members of the Enterobacteriaceae family. The disease has the highest mortality rate amongst bacterial enteric infections.
M. V. Abramtseva+2 more
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Non-capsular based immunization approaches to prevent Streptococcus pneumoniae infection
Streptococcus pneumoniae is a Gram-positive bacterium and the leading cause of bacterial pneumonia in children and the elderly worldwide. Currently, two types of licensed vaccines are available to prevent the disease caused by this pathogen: the 23 ...
Pedro H. Silva+14 more
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