Results 201 to 210 of about 291,495 (261)

Polysaccharides as vaccine adjuvants

Vaccine, 2018
Adjuvant is a substance added to vaccine to improve the immunogenicity of antigens, and it can induce stronger immune responses and reduce the dosage and production cost of vaccine in populations responding poorly to vaccination. Adjuvants in development or in use mainly include aluminum salts, oil emulsions, saponins, immune-stimulating complexes ...
Beini, Sun   +5 more
openaire   +2 more sources

CONJUGATED POLYSACCHARIDE VACCINES

Infectious Disease Clinics of North America, 1999
The joining of polysaccharide antigens to various proteins can result in increased immunogenicity of vaccines composed of such antigens. This article discusses conjugated polysaccharide vaccines for Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitis.
H, Ahmad, E K, Chapnick
openaire   +2 more sources

C-POLYSACCHARIDE IN A PNEUMOCOCCAL VACCINE

Acta Pathologica Microbiologica Scandinavica Series C: Immunology, 2009
The 14-valent pneumococcal vaccine, Pneumovax, was found to contain approximately 25o micrograms per ml of the cell-wall antigen, C-polysaccharide (C-Ps), in addition to 100 micrograms per ml of each of the 14 capsular polysaccharides. Rabbit anti-C-Ps antiserum recognized four components of this C-Ps with different antigenic determinants ...
U B, Sørensen, J, Henrichsen
openaire   +2 more sources

Pneumococcal Polysaccharide Vaccines

Clinical Infectious Diseases, 1989
Pneumococcal infections are major causes of morbidity and mortality in children throughout the world. For this reason and because of the increasingly frequent isolation of multiply resistant pneumococci of the serotypes most often causing infection in childhood, prophylactic immunization offers the best prospect of reducing the incidence of such ...
openaire   +2 more sources

Vaccines Against Polysaccharide Antigens

Current Drug Target -Infectious Disorders, 2001
Encapsulated bacteria such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae serogroup B (Hib) are a major cause of disease worldwide. Vaccine development against these organisms has targeted their capsular polysaccharides (CPS), as anti-capsular antibodies often protect against disease.
G B, Lesinski, M A, Westerink
openaire   +2 more sources

Polysaccharide Conjugate Typhoid Vaccine

New England Journal of Medicine, 2001
There is a growing appreciation of the huge health threat posed by increasingly resistant infectious diseases, especially in tropical areas of the developing world.
R L, Guerrant, M, Kosek
openaire   +2 more sources

Randomised revaccination with pneumococcal polysaccharide or conjugate vaccine in asplenic children previously vaccinated with polysaccharide vaccine

Vaccine, 2007
Asplenic children are at high risk of invasive pneumococcal infection. In this group, the American Academy of Pediatrics recommends a single revaccination with the 23-valent polysaccharide vaccine (PSV23) 3-5 years after a previous PSV23 dose. Despite potential advantages, there are few data available regarding the safety and immunogenicity of the ...
F, Smets   +6 more
openaire   +2 more sources

Efficacy of Pneumococcal Polysaccharide Vaccines

Clinical Infectious Diseases, 1981
due to pneumococcal infection. Estimates based on data obtained in this country after licensure of the vaccine suggest that the efficacy in certain groups may be low:
openaire   +2 more sources

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