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Capsular Polysaccharides as Vaccine Candidates
1990The discovery of a “specific soluble substance” secreted by pneumococci during growth (Dochez and Avery 1917) and the identification of this substance as a carbohydrate (Heidelberger and Avery 1923) were new and important developments in vaccine technology.
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Capsular Polysaccharides as Human Vaccines
1983Publisher Summary This chapter discusses the use of capsular polysaccharides as human vaccines. Vaccination has proved to be one of the most useful scientific developments in the control and eradication of human disease. Early vaccines were based on whole-organism preparations or on protein toxins isolated from different bacteria.
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Capsular polysaccharide vaccines today
Infection, 1984Polysaccharide (PS) vaccines are a relatively new class of antibacterial vaccines that have special advantages but also special problems related to their character. Several of them have proven very effective in preventing bacteremic infections caused by encapsulated bacteria such as meningococci, pneumococci and Haemophilus influenzae type b ...
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Chemically Modified Capsular Polysaccharides as Vaccines
1988Capsular polysaccharides have assumed an important role as vaccines against disease caused by bacteria in humans. The concept of using pure definable polysaccharides devoid of their accompanying complex bacterial mass is technically elegant and is obviously capable of extension into other areas of immunoprophylaxis.
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Polysaccharide Vaccines: A Perspective on Non-Typhoidal Salmonella
Polysaccharides, 2021Akosiererem Sokaribo +2 more
exaly
Bacterial Polysaccharide Vaccines
2011Capsulated bacteria, Gram-positive or Gram-negative, cause a variety of infections in man. Prominent among them are streptococci of Lancefield’s groups A, B, and C, staphylococci, meningococci, Haemophilus influenzae type b, klebsiellas, Escherichia coli, and Salmonella typhi, to name but some.
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Pneumococcal polysaccharide vaccines
The Indian Journal of Pediatrics, 1982openaire +2 more sources
[Polysaccharide subunit vaccines].
La Revue du praticien, 1995The polysaccharide capsules of many germs (pneumococcus, meningococcus, Haemophilus b, salmonella, etc.) can induce synthesis of protective antibodies in man. The development of many vaccines has been based on this phenomenon. Unfortunately, the polysaccharide antigens cannot trigger an immune response before the age of 2 years.
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