Results 31 to 40 of about 786,143 (326)
Safety, immunogenicity and dose ranging of a new Vi-CRM₁₉₇ conjugate vaccine against typhoid fever: randomized clinical testing in healthy adults. [PDF]
PLoS ONE, 2011 Typhoid fever causes more than 21 million cases of disease and 200,000 deaths yearly worldwide, with more than 90% of the disease burden being reported from Asia.
Pierre van Damme +13 more
doaj +1 more source
Polysaccharide responsiveness is not biased by prior pneumococcal-conjugate vaccination. [PDF]
PLoS ONE, 2013 Polysaccharide responsiveness is tested by measuring antibody responses to polysaccharide vaccines to diagnose for humoral immunodeficiency. A common assumption is that this responsiveness is biased by any previous exposure to the polysaccharides in the ...
Jens Magnus Bernth-Jensen +1 more
doaj +1 more source
Polysaccharide structure dictates mechanism of adaptive immune response to glycoconjugate vaccines
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Helper T cell responses to glycoconjugate vaccines are regulated through mechanisms dependent upon the structure of the polysaccharide. We show that three of the four important conjugate vaccines tested induced antibody responses regulated ...
XiMei Sun +3 more
semanticscholar +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 Infections caused by Streptococcus pneumoniae are relevant for Russia and the world. One of the key factors in the pathogenicity of pneumococcus is a polysaccharide capsule.
E. S. Petukhova +2 more
doaj +1 more source
Vaccine against Streptococcus suis Infection in Pig Based on Alternative Carrier Protein Conjugate
Vaccines, 2022 Streptococcus suis is a serious pathogen in the pig industry with zoonotic potential. With respect to the current effort to reduce antibiotic use in animals, a prophylactic measure is needed to control the disease burden.
Natalie Kralova +14 more
doaj +1 more source
Bacterial outer membrane vesicles and vaccine applications [PDF]
, 2014 Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo +10 more
core +2 more sources
Clinical and Vaccine Immunology, 2014 Meningococcal conjugate vaccines are today successfully deployed in universal programs for children and adolescents in different geographic regions to control meningitis and septicemia.
M. Ramasamy +9 more
semanticscholar +1 more source
Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine. [PDF]
, 2018 Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Although this is a vaccine preventable disease, S. pneumoniae still causes over 1 million deaths per year, mainly in children under the age of five.
Abouelhadid, Sherif +7 more
core +3 more sources
The Journal of Pediatric Pharmacology and Therapeutics, 2016 This review describes development of currently available pneumococcal vaccines, provides summary tables of current pneumococcal vaccine recommendations in children and adults, and describes new potential vaccine antigens in the pipeline.
Calvin C. Daniels +2 more
semanticscholar +1 more source
Efficacy of pneumococcal polysaccharide vaccine [PDF]
Canadian Medical Association Journal, 2009 Our commentary [1][1] was intended as a critical review of the evidence base provided by Anke Huss and colleagues’ meta-analysis. [2][2] We challenged what we perceived as an implied recommendation for countries to cease vaccination programs with polysaccharide pneumococcal vaccine for adults ...
Huss, A +4 more
openaire +2 more sources