Results 221 to 230 of about 467,932 (337)

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Extraction, Structural Characterization and Biological Activities of Polysaccharides Derived From <i>Hericium erinaceus</i>. [PDF]

Food Sci Nutr
Sun N, Li C, Liang W, Wu Z, Han X, Xu S.
europepmc   +1 more source

Rice bran-nonstarch polysaccharide in broiler chick diets : Anticipation on its antinutritive effects

, 2002
Adrizal
openalex   +1 more source

A Mycoplasma strain F38 growth-inhibiting monoclonal antibody (WM-25) identifies an epitope on a surface-exposed polysaccharide antigen [PDF]

, 1995
Fred R. Rurangirwa, A. Wambugu, S M Kihara, T C McGuire   +3 more
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Marine Macroalgal Polysaccharides in Nanomedicine: Blue Biotechnology Contributions in Advanced Therapeutics. [PDF]

Molecules
Geetha Bai R, Sudheer S, Premarathna AD, Tuvikene R.   +3 more
europepmc   +1 more source

Structure and Biosynthetic Gene Cluster of Sulfated Capsular Polysaccharide from the Marine Bacterium Vibrio sp. KMM 8419 [PDF]

Maxim S. Kokoulin, Yulia V. Savicheva, Nadezhda Otstavnykh, Valeriya V. Kurilenko, Dmitry Meleshko, Marina P. Isaeva   +5 more
openalex   +1 more source

Engineering Dimensional Configuration of Single‐Atom S‐Cu‐S Sites as Reversible Electron Station for Enhanced Peroxidase‐Mimicking

Advanced Science, EarlyView.
L‐cysteine triggers auto‐assembly of POD‐like 3D biomimetic S‐Cu‐S single‐atom nanozymes on MoS2 (MoCC). MoCC shows 16.3‐fold higher catalytic velocity and 17.9‐fold greater affinity than HRP, enabling efficient •OH generation via enhanced electron inversion and transfer.
Wenjie Ma, Qian He, Jiancheng Sun, Yiqing Chen, Hongfei Su, Ludan Zhang, Xiao He, Yuguang Wang, Changjian Xie, Zhiyong Zhang, Xin Zhou, Yuliang Zhao, Wenyan Yin   +12 more
wiley   +1 more source

Fabrication of Algal Polysaccharides-Based Nanoparticles and Evaluation of Their Antioxidant and Anti-Inflammatory Potential. [PDF]

IET Nanobiotechnol
Chen CY, Huang WH, Tsai PY, Huang CH.
europepmc   +1 more source

Dendrobium officinale polysaccharide-EGCG complexes: Covalent and non-covalent interactions for enhanced antioxidant properties

Xiaoke Peng, Xiaojia Yan, David Julian McClements, Shuai Chen, Cuicui Ma, Xuebo Liu, Guoqiang Zhang, Fuguo Liu   +7 more
openalex   +1 more source