Results 81 to 90 of about 257,706 (241)

Gas Chromatographic Determination of 1,4-Dioxane in Polysorbate 60 and Polysorbate 80

Journal of AOAC INTERNATIONAL, 1979
Abstract A gas chromatographic method is presented for the quantitative determination of 1,4- dioxane in polysorbate 60 and polysorbate 80. Dioxane is isolated from the matrix by closedsystem vacuum distillation with water as the carrier solvent.
Thomas Fazio, Charles R Warner, Thomas J Birkel   +2 more
openaire   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source

Surfactant‐Modified Progesterone‐Loaded PVP/Cellulose Fibres for Future Drug Delivery Applications in Menopause

Macromolecular Materials and Engineering
Menopause often results in symptoms that impact physical and mental well‐being, and hormone replacement therapy (HRT) using progesterone (PGS) is a common treatment.
Omar Shafi, Michelle Swer, Un Hou Chan, Alisha Kassam, Mirkomol Mirzarakhimov, Jai Yi Huang, F Brako   +6 more
doaj   +1 more source

The effect of the composition of polysorbate 80 grades on their physicochemical properties.

Journal of Excipients and Food Chemicals, 2021
Polysorbate 80 is one of the most commonly used surfactants in the formulation of biotherapeutics, particularly those administered intravenously. It comprises a mixture of fatty acids but is not a precisely defined chemical entity.
Gayathri Kollamaram, Gareth Williams
doaj  

Bio-inspired artemether-loaded human serum albumin nanoparticles for effective control of malaria-infected erythrocytes [PDF]

, 2016
Aim: The intra-erythrocytic development of the malarial parasite is dependent on active uptake of nutrients, including human serum albumin (HSA), into parasitized red blood cells (pRBCs).
Aditi A Sidhaye, Bodammer JE, Chairpan S, Ginsburg H, Kamalinder K Singh, Kanchan C Bhuran, Munna Abubaker, Niroshini Nirmalan, Read M, Sneha Zambare, Yuthavong Y   +10 more
core   +2 more sources

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in Monoclonal Antibody Formulation

Pharmaceuticals
Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they are prone to degradation, which results in unwanted impurities.
Jiayi Huang, Shiqi Hong, Lucas Yuan Hao Goh, Hailong Zhang, Tao Peng, Keat Theng Chow, Rajeev Gokhale, Vinod Tuliani   +7 more
doaj   +1 more source

Approximating Pareto frontier using a hybrid line search approach [PDF]

, 2010
This is the post-print version of the final paper published in Information Sciences. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting ...
Ajith Abraham, Batanović, Chen, Crina Grosan, Das, Das, Das, Deb, Deb, Ehrgott, Ehrgott, Grosan, Ho, Huband, Jahn, Lewis, Messac, Messac, Messac, Messac, Messac, Messac, Messac, Messac, Messac, Miettinen, Okabe, Ortiz, Protter, Rueda, Ruzika, Sanchis, Sayın, Tripathi, Veldhuizen, Wang   +35 more
core   +3 more sources

Effects of Common Food Additives Kappa‐, Iota‐ and Lambda‐Carrageenans on Intestinal Epithelial Cell Activation and Barrier Disruption

Clinical &Experimental Allergy, EarlyView.
Carrageenans, widely used food additives, disrupted intestinal epithelial integrity in a gut‐on‐a‐chip model. All types (κ‐, ɩ‐, λ‐) induced cytotoxicity, inflammation and tight junction (TJ) disruption, triggering TNF‐mediated immune responses. λ‐Carrageenan had the most severe effects, supporting the Epithelial Barrier Theory linking food additives ...
Na Sun, Yagiz Pat, Huseyn Babayev, Sena Ardicli, Ismail Ogulur, Xianting Bu, Manru Li, Shuqi Jia, Beate Rückert, Raja Dhir, Kari C. Nadeau, Mubeccel Akdis, Cezmi A. Akdis, Duygu Yazici   +13 more
wiley   +1 more source

Alterations of bone proteins in medication‐related osteonecrosis of the jaw

European Journal of Oral Sciences, Volume 133, Issue 2, April 2025.
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert, Phillipp Brockmeyer, Philipp Kauffmann, Jan Wiegel, Florian Lautenbacher, Nicolai Miosge, Boris Schminke   +6 more
wiley   +1 more source