Results 81 to 90 of about 250,055 (193)

DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling

Aging Cell, Volume 25, Issue 9, September 2026.
In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li, Zhen Yang, Wukaiyang Liang, Jie Huang, Tianyi Ji, Hao Nie, Zixin Wan, Yuqi Qiu, Yi Huang, Le Zhang, Cuntai Zhang, Jinhua Yan   +11 more
wiley   +1 more source

An overlooked environmental risk of a widely used non-ionic surfactant: Environmental toxicological effects of polysorbate 20 across life stages of the freshwater snail Biomphalaria glabrata

Ecotoxicology and Environmental Safety
Polysorbate 20 (Tween 20) is a widely used non-ionic surfactant applied in food, pharmaceutical, and experimental research fields. However, information on its potential effects on freshwater organisms across different life stages remains limited. In this
Jiyuan Wang, Xianwei Li, Jialu Xu, Hairun Li, Hao Wu, Ruke Wang, Yuqing Shao, Yuzi Zhou, Xiaodong Yao, Lailing Du, Huiliang Zou, Hongyu Li, Lijun Lin   +12 more
doaj   +1 more source

Prospective Trial on Tolerability and Efficacy of Adjuvant Nedaplatin Plus Docetaxel for Non‐Small Cell Lung Cancer

Cancer Science, Volume 117, Issue 9, Page 2535-2542, September 2026.
The flow of this trial and the treatment schedule of adjuvant chemotherapy with nedaplatin plus docetaxel for completely resected non‐small cell lung cancer (NSCLC) (A). The primary endpoint of this study was tolerability, assessed by the completion rate of the planned four chemotherapy cycles. As a result, it was 74.3%, exceeding that reported for the
Koji Teramoto, Ryosuke Kaku, Tomoyuki Igarashi, Masayuki Hashimoto, Shoji Kitamura, Makoto Motoishi, Yuji Suzumura, Satoru Sawai, Yataro Daigo, Jun Hanaoka   +9 more
wiley   +1 more source

Impact of Polysorbate 80 on the Antimicrobial Activity of Oregano and Thyme

Molecules
Plant-derived essential oils (EOs) possess significant antimicrobial potential against spoilage and pathogenic microorganisms. However, their efficacy can vary depending on the test method, making it difficult to standardise results.
Marta Carvalho, Joana Barbosa, Marcelo Belchior Rosendo da Silva, Helena Albano, Paula Teixeira   +4 more
doaj   +1 more source

From Composition to Function: Defining Functional Equivalence in Plant‐Based Meat Analogs

Sustainable Food Proteins, Volume 4, Issue 3, September 2026.
Akila Srinivasagam Ramasamy Venkateswaran, Ciara K. McDonnell   +1 more
wiley   +1 more source

Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles

International Journal of Nanomedicine, 2011
Xin-Hua Tian1, Xiao-Ning Lin1, Feng Wei1, Wei Feng1, Zhi-Chun Huang1, Peng Wang1, Lei Ren2, Yi Diao11Department of Neurosurgery, Zhongshan Hospital of Xiamen University, Xiamen, People's Republic of China; 2Research Center of Biomedical ...
Xin-Hua Tian, Xiao-Ning Lin, Feng Wei, et al   +3 more
doaj  

Development of Polysorbate 80/Phospholipid mixed micellar formation for docetaxel and assessment of its in vivo distribution in animal models

Nanoscale Research Letters, 2011
Docetaxel (DTX) is a very important member of taxoid family. Despite several alternative delivery systems reported recently, DTX formulated by Polysorbate 80 and alcohol (Taxotere®) is still the most frequent administration in clinical practice.
Geng Hongquan, Wang Juan, Peng Xia, Song Hua, Ruan Jing, Wang Kan, Bao Chenchen, Zhang Xueqing, Cui Daxiang   +8 more
doaj  

Persistent Hyperpigmentation Following Coretox Injection: A Review of Adverse Events Associated with Polysorbate 20. [PDF]

Plast Reconstr Surg Glob Open
Kim JS.
europepmc   +1 more source

The effect of the composition of polysorbate 80 grades on their physicochemical properties.

Journal of Excipients and Food Chemicals
Polysorbate 80 is one of the most commonly used surfactants in the formulation of biotherapeutics, particularly those administered intravenously. It comprises a mixture of fatty acids but is not a precisely defined chemical entity.
Gayathri Kollamaram, Gareth R. Williams
doaj  

Comment on Honndorf et al. Comparative Analytics and Pharmacodynamics of the Complex Protein-Free Botulinum Toxin Type A Formulations DaxibotulinumtoxinA, IncobotulinumtoxinA and RelabotulinumtoxinA. <i>Toxins</i> 2026, <i>18</i>, 142. [PDF]

Toxins (Basel)
Ståhl U, Hamnevik E, Liljegren Sundberg Å, Persson C, Prygova I.   +4 more
europepmc   +1 more source