Results 71 to 80 of about 257,706 (241)

An Analytical Method for Detecting Toxic Metal Cations Using Cyclotriveratrylene Derivative Capped Gold Nanoparticles [PDF]

, 2015
Cyclotriveratrylene-oxime (CTV-oxime) derivatives that terminate with a dithiolate linker were synthesized enabling the supramolecular scaffold to adhere to gold nanoparticles (AuNPs) with the bowl-shaped cavity of the CTV scaffold exposed for ...
Becker, Daniel P., Holz, Richard C., Osner, Zachary R.   +2 more
core   +3 more sources

Transmission Raman Spectroscopy (TRS) for Accurate Authentication of API in Coated Hydroxychloroquine (HCQ) Tablets

Journal of Raman Spectroscopy, EarlyView.
We report the development and use of a transmission Raman spectroscopy (TRS) system for a more accurate but nonintrusive way of authentication of API in coated HCQ tablets which otherwise is not possible using the backscattered (BS) configuration of Raman spectroscopy. The coating interference is found to be almost zero in case of the TRS and a greater
Vijay Kumar, Khan Mohammad Khan, Hemant Krishna, Khageswar Sahu, Srinibas Satapathy, Shovan Kumar Majumder   +5 more
wiley   +1 more source

The Allium cepa Derived Compound Propyl Propane Thiosulfonate (PTSO) Improves Tumorigenesis Due to Its Immunomodulatory Effect: A Preclinical Study

Phytotherapy Research, EarlyView.
In vitro and in vivo effects of PTSO in colorectal cancer preclinical models, highlighting antiproliferative, pro‐apoptotic, barrier‐enhancing, antitumor, prebiotic and immunomodulatory properties. Created using BioRender. ABSTRACT Allium‐derived organosulfur compounds offer significant health benefits.
María Jesús Rodríguez‐Sojo, Laura Hidalgo‐García, Jose Alberto Molina‐Tijeras, Laura López‐Escanez, Luckman Gbati, Teresa Vezza, Patricia Diez‐Echave, Antonio Jesús Ruiz‐Malagón, Jorge García‐García, Federico García, Alberto Baños, Lidia Gil‐Martínez, Rocío López‐Posadas, Markus F. Neurath, Julio Gálvez, María Elena Rodríguez‐Cabezas, Alba Rodríguez‐Nogales   +16 more
wiley   +1 more source

Possibilities of microemulsion application in rectal administration of indomethacin

European Pharmaceutical Journal, 2021
Rectal administration is a suitable route of administration for drugs that are either very irritating to the intestine (e.g., indomethacin) or are more effective when the first-pass effect in the liver is circumvented.
Špaglová M., Čuchorová M., Čierna M., Mikušová V., Bauerová K., Poništ S.   +5 more
doaj   +1 more source

Effects of detergents on activity, thermostability and aggregation of immobilized lipases [PDF]

, 2014
Predmetom tejto diplomovej práce bolo štúdium vplyvu detergentov na aktivitu, termostabilitu a agregáciu voľnej a imobilizovanej formy komerčného preparátu lipázy izolovanej z mikroskopickej huby Rhizopus arrhizus. Teoretická časť obsahuje ucelenú rešerš
Bančáková, Anna
core  

The Molecular Chaperone α-Crystallin as an Excipient in an Insulin Formulation [PDF]

, 2010
PURPOSE: To investigate insulin fibrillation under accelerated stress conditions in the presence of a novel excipient, the molecular chaperone α-crystallin, in comparison with common excipients. METHODS: To induce fibrillation, recombinant human insulin (
Marco van de Weert, Ruedeeporn Tantipolphan, Tue Rasmussen, Wim Jiskoot   +3 more
core   +2 more sources

Activating Paper Applying Gelatin, Starch and Chitosan Coatings Loaded With O/W Emulsions Encapsulating Rutin, Carvacrol and α‐Tocopherol

Packaging Technology and Science, EarlyView.
Emulsion type governed the microstructure and functionality of papers coated with biopolymers matrix loaded with hydrophobic bioactives encapsulated into O/W emulsions. Emulsified systems improved UV–Vis barrier and antioxidant activity, whereas gelatin coatings with conventional or Pickering emulsions provided the greatest mechanical reinforcement ...
Kamila de L. Santos, Ana Mônica Quinta Barbosa Bittante, Rodrigo Vinícius Lourenço, Júlio Cesar de Carvalho Balieiro, Paulo José do Amaral Sobral   +4 more
wiley   +1 more source

Construction of Spleen-Accumulated Polysorbate 20-Containing Ionizable Lipid Nanoparticles for mRNA Delivery

Nanomaterials
Messenger RNA therapy represents a transformative therapeutic in vaccine development, tumor immunotherapy, and genetic disease intervention. Polyethylene glycol (PEG) lipid, a key component of ionizable lipid nanoparticles (iLNPs) for mRNA delivery, and ...
Hanyu Liu, Siqi Li, Kexin Chen, Shuyi Yao, Xuefeng Tang, Xiaojun Han   +5 more
doaj   +1 more source

EFFECT OF DIFFERENT NON IONIC SURFACTANTS ON THE IN-VITRO RELEASE RATE OF A NON STEROIDAL ANTI-INFLAMMATORY DRUG FROM SOME LIPOPHILIC SUPPOSITORY BASES

Zagazig Journal of Pharmaceutical Sciences, 2011
Formulation of tolmetin sodium suppositories was carried out using different lipophilic bases as Novatta, suppocir NA10. suppocir W35, suppocir AM, Witepsol E75 and Witepsol H15. The in vitro release study of 200 mg tolmetin sodium suppository from these
Sayed Auda , Mahmoud Ahmed , S. Abd El-Rasoul   +2 more
doaj   +1 more source

Structural Profiling of Lipid Nanoparticles at Sub‐10 nm Resolution via AF4 Coupled Online to SAXS and SANS

Small Methods, EarlyView.
Dilution‐controlled AF4 coupled with SAXS and, for the first time, SANS enables high‐resolution characterization of non‐spherical lipid nanoparticles. Enhanced scattering contrast and D2O‐based measurements resolve particle features down to ∼5 nm and reveal shape distributions.
Eva Bittrich, Susanne Boye, Zanelle Van Niekerk, Zahn Stanvliet, Arthur Porfetye, Fátima Herranz‐Trillo, Hans Bolinsson, Stefaniya Gaydarova, Christo Tzachev, Anne Martel, Lars Nilsson, Ralf Schweins, Albena Lederer   +12 more
wiley   +1 more source