Results 51 to 60 of about 250,055 (193)

Construction of Spleen-Accumulated Polysorbate 20-Containing Ionizable Lipid Nanoparticles for mRNA Delivery

open access: yesNanomaterials
Messenger RNA therapy represents a transformative therapeutic in vaccine development, tumor immunotherapy, and genetic disease intervention. Polyethylene glycol (PEG) lipid, a key component of ionizable lipid nanoparticles (iLNPs) for mRNA delivery, and ...
Hanyu Liu   +5 more
doaj   +1 more source

The BioSAXS laboratory of the ITACA.SB Research Infrastructure

open access: yesJournal of Applied Crystallography, EarlyView.
We present a versatile state‐of‐the‐art X‐ray scattering laboratory within the ITACA.SB Research Infrastructure, enabling multi‐scale structural characterization of complex biological specimens and advanced materials through integrated small‐ and wide‐angle X‐ray scattering (SAXS/WAXS) techniques.
Francesco Scattarella   +8 more
wiley   +1 more source

EFFECT OF DIFFERENT NON IONIC SURFACTANTS ON THE IN-VITRO RELEASE RATE OF A NON STEROIDAL ANTI-INFLAMMATORY DRUG FROM SOME LIPOPHILIC SUPPOSITORY BASES

open access: yesZagazig Journal of Pharmaceutical Sciences, 2011
Formulation of tolmetin sodium suppositories was carried out using different lipophilic bases as Novatta, suppocir NA10. suppocir W35, suppocir AM, Witepsol E75 and Witepsol H15. The in vitro release study of 200 mg tolmetin sodium suppository from these
Sayed Auda   +2 more
doaj   +1 more source

Behavioural responses of peach potato aphid, Myzus persicae Sulzer (Hemiptera: Aphididae), to entomopathogenic fungi infected conspecifics

open access: yesAgricultural and Forest Entomology, EarlyView.
Myzus persicae showed no detectable behavioural response to Beauveria bassiana‐colonised agar alone. Aphids spent significantly more time in odour fields containing EPF‐infected conspecifics than healthy aphids, agar or blank air. EPF infection may alter host‐associated odours, suggesting pathogen‐mediated cues could influence aphid behaviour and ...
Ben J. Clunie   +6 more
wiley   +1 more source

Surfactant‐Modified Progesterone‐Loaded PVP/Cellulose Fibres for Future Drug Delivery Applications in Menopause

open access: yesMacromolecular Materials and Engineering
Menopause often results in symptoms that impact physical and mental well‐being, and hormone replacement therapy (HRT) using progesterone (PGS) is a common treatment.
Omar Shafi   +6 more
doaj   +1 more source

The External Exposome and Food Allergy: How Environmental Exposures Shape Disease Risk

open access: yesAllergy, EarlyView.
ABSTRACT IgE‐mediated food allergy is a global health issue with rising prevalence that cannot be explained by genetic change alone, strongly suggesting that environmental exposures are a key driver. The external exposome encompasses several exposures that influence the developing immune system and modify food allergy risk.
Johanna M. Smeekens   +5 more
wiley   +1 more source

The effect of the composition of polysorbate 80 grades on their physicochemical properties.

open access: yesJournal of Excipients and Food Chemicals, 2021
Polysorbate 80 is one of the most commonly used surfactants in the formulation of biotherapeutics, particularly those administered intravenously. It comprises a mixture of fatty acids but is not a precisely defined chemical entity.
Gayathri Kollamaram, Gareth Williams
doaj  

Alterations of bone proteins in medication‐related osteonecrosis of the jaw

open access: yesEuropean Journal of Oral Sciences, Volume 133, Issue 2, April 2025.
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert   +6 more
wiley   +1 more source

Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in Monoclonal Antibody Formulation

open access: yesPharmaceuticals
Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they are prone to degradation, which results in unwanted impurities.
Jiayi Huang   +7 more
doaj   +1 more source

Potential of organogel‐based colloidal hydrogels for new cosmetic formulations

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Colloidal hydrogels are formed by combining anionic, cationic, or nonionic surfactants with two oils of cosmetic interest: sweet almond oil and phytosqualane. These systems are obtained through hot emulsification followed by cooling, which leads to the aggregation of gel‐like particles.
Andrea Gregorio Gomes   +5 more
wiley   +1 more source

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