Results 41 to 50 of about 257,706 (241)

Tolerance of Pseudomonas aeruginosa in in vitro biofilms to high level peracetic acid disinfection [PDF]

, 2017
Biofilm has been suggested as a cause of disinfection failures in flexible endoscopes where no lapses in the decontamination procedure can be identified. To test this theory, the activity of peracetic acid (PAA), one of the commonly used disinfectants in
Akinbobola, Ayorinde, Mckay, William G., Ramage, Gordon, Sherry, Leighann, Williams, Craig   +4 more
core   +3 more sources

LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate [PDF]

, 2016
Background Lrrk2, a gene linked to Parkinson\u2019s disease, encodes a large scaffolding protein with kinase and GTPase activities implicated in vesicle and cytoskeletal-related processes.
Arrigoni, Giorgio, Belluzzi, Elisa, Beltramini, Mariano, Bubacco, Luigi, Carrion, Maria Per\ue8z, Cirnaru, Maria Daniela, Civiero, Laura, Cogo, Susanna, Franchin, Cinzia, Gonnelli, Adriano, Greggio, Elisa, Marte, Antonella, Onofri, Franco, Piccoli, Giovanni, Plotegher, Nicoletta, Russo, Isabella   +15 more
core   +5 more sources

Effect of food additives on key bacterial taxa and the mucosa-associated microbiota in Crohn’s disease. The ENIGMA study

Gut Microbes, 2023
Food additives have been linked to the pro-inflammatory microbial dysbiosis associated with Crohn’s disease (CD) but the underlying ecological dynamics are unknown.
J.J. Jimenez Loayza, S. Kang, L. Schooth, J. J. Teh, A. de Klerk, E. K. Noon, J. Zhang, J. Hu, A. L. Hamilton, A. Wilson-O’Brien, G. L. Trakman, W. Lin, J. Ching, L. Or, J.J.Y. Sung, J. Yu, S.C. Ng, M.A. Kamm, M. Morrison   +18 more
doaj   +1 more source

A patient preference study that evaluated fluticasone furoate and mometasone furoate nasal sprays for allergic rhinitis [PDF]

, 2016
Background: Corticosteroid nasal sprays are the mainstay of treatment for allergic rhinitis. These sprays have sensory attributes such as scent and/or odor, taste and aftertaste, and run down the throat and/or the nose, which, when unpleasant, can affect
Bremner, P, Dimitroff, A, Johnson, N, Luscombe, G, Prillaman, B, Rhee, C, Yanez, A   +6 more
core   +2 more sources

Time‐course characterization of intraocular pressure in murine steroid‐induced ocular hypertension: Effects of route, schedule, and concentration

Animal Models and Experimental Medicine, EarlyView.
Steroid‐induced ocular hypertension is a useful mouse model for glaucoma, but published work rarely quantifies how route, dose, and schedule shape the intraocular pressure (IOP) time‐course—hindering reproducibility and forcing labs to pilot protocols.
Nicholas Y. Q. Tan, Sai Bo Bo Tun, Hla Myint Htoon, Veluchamy Amutha Barathi, Tina T. Wong   +4 more
wiley   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source

Torque measurement in real time during mixing and kneading of bread dough with high content of resistant maize starch and enzymes [PDF]

, 2016
In this work, a methodology to measure torque during dough mixing in large scale was developed and the baking performance of bread dough formulated with resistant starch (RS) and enzymes was evaluated.
Altuna, Luz, Pileggi, Rafael G., Ribotta, Pablo Daniel, Romano, Roberto C. O., Tadini, Carmen C.   +4 more
core   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Interface Compositions as Determinants of Resveratrol Stability in Nanoemulsion Delivery Systems

Foods, 2020
The incorporation of hydrophobic ingredients, such as resveratrol (a fat-soluble phytochemical), in nanoemulsions can increase the water solubility and stability of these hydrophobic ingredients.
Adela Mora-Gutierrez, Rahmat Attaie, Maryuri T. Núñez de González, Yoonsung Jung, Sixto A. Marquez   +4 more
doaj   +1 more source

Characterization of radicals in polysorbate 80 using electron paramagnetic resonance (EPR) spectroscopy and spin trapping

International Journal of Pharmaceutics: X, 2022
Polysorbates are an important class of nonionic surfactants that are widely used to stabilize biopharmaceuticals. The degradation of polysorbate 20 and 80 and the related particle formation in biologics are heavily discussed in the pharmaceutical ...
Judith J. Mittag, Marie-Luise Trutschel, Helen Kruschwitz, Karsten Mäder, Julia Buske, Patrick Garidel   +5 more
doaj   +1 more source