Results 151 to 160 of about 320,368 (261)

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

Elovl7 sensitizes podocytes to ferroptosis in podocytopathy by elongating polyunsaturated fatty acids. [PDF]

Cell Death Dis
Kang M, Zhan X, Huang X, Zhao Y, Wang X, Li Q, Zhu J, Liu F, Li M, Bai L, Wen J, Wang X, Zhou L, Wei R, Qing J, Yan P, Lu M, Mao J, Wu J.   +18 more
europepmc   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

The Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

Polyunsaturated Fatty Acids and Skin Cancer: Two-Sample Mendelian Randomization Study. [PDF]

Ann Dermatol
Kim G, Kim BR, Paik K, Jin SP, Park H, Myung W, Lee JK, Choi CW, Kim J.   +8 more
europepmc   +1 more source

Multistressor Interaction of Perfluorooctane Sulfonate (PFOS) and Temperature in Two Estuarine Fish Species, Red Drum (Sciaenops ocellatus) and Sheepshead Minnow (Cyprinodon variegatus)

Environmental Toxicology, EarlyView.
ABSTRACT Perfluorooctane sulfonate (PFOS), a perfluoroalkyl substance (PFAS), is characterized by a long, fluorinated carbon chain which makes it ideal for oil‐ and water‐repellent products but detrimental for the environment, where it persists and accumulates in organisms.
Anna L. Thornton, Katy W. Chung, Peter B. Key, Emily C. Pisarski, Philip Tanabe, Marie E. DeLorenzo   +5 more
wiley   +1 more source

Skeletal muscle disuse atrophy: protection by omega-3 polyunsaturated fatty acids. [PDF]

NFS J
Obrosov O, Coppey LJ, Davidson EP, Ebert SM, Adams CM, Yorek MA.   +5 more
europepmc   +1 more source

Synergistic and Antagonistic Effects of Chemical Pollutants and Parasitic Fungi on Cyanobacterial Metabolism

Environmental Toxicology, EarlyView.
ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz, Jutta Fastner, Stephanie Spahr, Justyna Wolinska   +3 more
wiley   +1 more source

Enhanced lipid metabolism serves as a metabolic vulnerability to polyunsaturated fatty acids in glioblastoma. [PDF]

JCI Insight
Kant S, Zhao Y, Kesarwani P, Alka K, Oyeniyi JF, Mohammad G, Ashrafi N, Graham SF, Miller CR, Chinnaiyan P.   +9 more
europepmc   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves, Priscila M. O. Muniz Cunha, Shênia Patrícia Corrêa Novo, Lorena Oliveira Souza Soares, Tatiana Dillenburg Saint‐Pierre, Fábio Veríssimo Correia, André Luís de Sá Salomão, Rachel Ann Hauser‐Davis, Enrico Mendes Saggioro   +8 more
wiley   +1 more source

Balanced polyunsaturated fatty acids diet prevents the D-galactose-induced neuroinflammation and cognitive impairments. [PDF]

Neurosci Appl
Marniquet I, Dupont-Viratelle J, Crespo F, Séré A, Layé S, Delpech JC.   +5 more
europepmc   +1 more source