Results 171 to 180 of about 439,320 (307)

Compound‐Specific Stable Isotope Analysis Improves the Association Between Dairy Fatty Acid Biomarkers and Dairy Intake: A Secondary Analysis

Lipids, EarlyView.
ABSTRACT Increasing evidence suggests that dairy consumption may decrease the risk of chronic diseases. However, this association remains unclear due to methodological limitations. As a part of a secondary analysis, we used compound‐specific stable isotope analysis to increase the accuracy of the dairy FA biomarkers (15:0, 17:0), considering that each ...
Camilla Parzanini, Marisa Soo, Shirley Vien, Ji‐Eun Chon, Anthony J. Hanley, Priya Kathirvel, Bohdan Luhovyy, G. Harvey Anderson, Richard P. Bazinet   +8 more
wiley   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Elovl7 sensitizes podocytes to ferroptosis in podocytopathy by elongating polyunsaturated fatty acids. [PDF]

Cell Death Dis
Kang M, Zhan X, Huang X, Zhao Y, Wang X, Li Q, Zhu J, Liu F, Li M, Bai L, Wen J, Wang X, Zhou L, Wei R, Qing J, Yan P, Lu M, Mao J, Wu J.   +18 more
europepmc   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

Balanced polyunsaturated fatty acids diet prevents the D-galactose-induced neuroinflammation and cognitive impairments. [PDF]

Neurosci Appl
Marniquet I, Dupont-Viratelle J, Crespo F, Séré A, Layé S, Delpech JC.   +5 more
europepmc   +1 more source

Elevation of Stearoyl‐Coenzyme A Desaturase and Monounsaturated Fatty Acids in Parkinson's Disease Serum

Movement Disorders, EarlyView.
Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik, Russell Pickford, Michelle Chua, Simon J.G. Lewis, Nicolas Dzamko, Woojin Scott Kim   +5 more
wiley   +1 more source

Polyunsaturated Fatty Acids and Skin Cancer: Two-Sample Mendelian Randomization Study. [PDF]

Ann Dermatol
Kim G, Kim BR, Paik K, Jin SP, Park H, Myung W, Lee JK, Choi CW, Kim J.   +8 more
europepmc   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source

Skeletal muscle disuse atrophy: protection by omega-3 polyunsaturated fatty acids. [PDF]

NFS J
Obrosov O, Coppey LJ, Davidson EP, Ebert SM, Adams CM, Yorek MA.   +5 more
europepmc   +1 more source

From wild to tamed: Reimagining novel crops through omics and local plant diversity

PLANTS, PEOPLE, PLANET, EarlyView.
The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá, Pablo D. Cárdenas   +1 more
wiley   +1 more source