Results 121 to 130 of about 408,067 (295)

Synthesis of Benzopyran Atropisomers via Electrophilic Halogenation

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
We report a halogenation‐based method for the synthesis of axially chiral benzopyrans, tolerating diverse substituents and halogens (Br, Cl, and I). A double bromination gives bisbenzopyrans with two stereogenic axes. Preliminary enantioselective conditions yield benzopyran atropisomer with up to 56% ee.
Alix Bourhis   +3 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi   +6 more
wiley   +1 more source

Clinicopathological and epigenetic differences between primary neuroendocrine tumors and neuroendocrine metastases in the ovary

open access: yesThe Journal of Pathology: Clinical Research
Currently, the available literature provides insufficient support to differentiate between primary ovarian neuroendocrine tumors (PON) and neuroendocrine ovarian metastases (NOM) in patients.
Merijn CF Mulders   +8 more
doaj   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

open access: yesExploration, EarlyView.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng   +11 more
wiley   +1 more source

Sistema di Analisi, Divulgazione e Utilizzo delle Informazioni geospaziali dei borghi della Campania per il supporto del Turista

open access: yesGEOmedia, 2012
Oggi, grazie ad una notevole evoluzione nel mondo dell’Osservazione della Terra, sia da remoto che “On Site”, la disponibilità di dati ed informazioni è cresciuta in modo del tutto rilevante e spesso ci si trova non più di fronte al problema di avere ...
Dimitri Dello Buono, Marco Bruno
doaj  

Antioxidant and Cytotoxic Properties of Piper spp. Volatile Oils That Inhibit Pathogenic Microorganisms

open access: yesFlavour and Fragrance Journal, EarlyView.
The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira   +11 more
wiley   +1 more source

Study Analisis Prestasi Atlet Karate Sulawesi Selatan [PDF]

open access: yes, 2018
Karate merupakan salah salah satu cabang olahraga yang paling diandalkan di Provinsi Sulawesi Selatan. Raihan medali dalam setiap pertandingan selalu menunjukkan prestasi yang luar biasa, sehingga provinsi Sulawesi Selatan selalu di perhitungkan oleh ...
ABADI, RESKY ANA
core  

Effectiveness of integrated shrub management and restoration techniques for rehabilitating shrub‐encroached rangelands of South Africa

open access: yesGrassland Research, EarlyView.
Herbaceous plant recovery following shrub clearing and reseeding in the rangelands of Peddie, Eastern Cape of South Africa. CTL, control; CO, cutting only; CR, cutting and reseeding; UPO, uprooting only; UPR, uprooting and reseeding. Abstract Background Shrub encroachment (SE) drives rangeland degradation, threatening biodiversity and forage ...
Monelisi Makanya   +3 more
wiley   +1 more source

Exploring the Relationship between Canine Paraoxonase-1 (PON-1) Serum Activity and Liver Disease Classified by Clinico-Pathological Evaluation

open access: yesAnimals
Paraoxonase-1 (PON-1), a liver-synthesized enzyme, acts as a negative acute-phase reactant during systemic inflammation in dogs. Given the hepatic synthesis of this enzyme, the presence of liver diseases may influence PON-1, thus affecting its ...
Sara Meazzi   +4 more
doaj   +1 more source

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