Results 91 to 100 of about 117,351 (307)

Modelagem e otimização de sistemas de lagoas de estabilização para tratamento de dejetos suinos [PDF]

, 1997
Tese (Doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de ProduçãoOs sistemas de tratamento de dejetos de suínos se revestem de grande importância sanitária, tendo em vista o intenso ...
Medri, Waldir
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A Knowledge Discovery in Motion Sickness: A Comprehensive Literature Review

IEEE Access, 2019
Motion sickness is a common perturbation experienced by humans in response to motion stimuli. The motion can happen in either real or virtual environments perceived by the vestibular system and visual illusion. The extensive varieties of research studies
Afsaneh Koohestani, Darius Nahavandi, Houshyar Asadi, Parham M. Kebria, Abbas Khosravi, Roohallah Alizadehsani, Saeid Nahavandi   +6 more
doaj   +1 more source

Review of best management practices for aquatic vegetation control in stormwater ponds, wetlands, and lakes [PDF]

, 2013
Auckland Council (AC) is responsible for the development and operation of a stormwater network across the region to avert risks to citizens and the environment.
Champion, Paul, McBride, Chris G., de Winton, Mary, Jones, Hannah Frances Emily, Özkundakci, Deniz, Edwards, Tracey, Clayton, John, Hofstra, Deborah, Rowe, David K., Wells, Rohan, Hamilton, David P.   +10 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Seasonally loaded waste stabilisation ponds: a novel application for intermittent discharge [PDF]

, 2012
This research examined the use of a single facultative pond for treatment of an intermittent discharge from a UK campsite. The system was monitored over an 11-month period to determine the optimum time for discharge in terms of quality standards.
Salter, A.M., Whalley, C.P., Banks, C.J., Heaven, S.   +3 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Process‐Based Atmosphere‐Hydrology‐Malaria Modeling: Performance for Spatio‐Temporal Malaria Transmission Dynamics in Sub‐Saharan Africa

Water Resources Research
With the goal of eradication by 2030, Malaria poses a significant health threat, profoundly influenced by meteorological and hydrological conditions. In support of malaria vector control efforts, we present a high‐resolution, coupled physically‐based ...
Mame Diarra Bousso Dieng, Adrian M. Tompkins, Joël Arnault, Ali Sié, Benjamin Fersch, Patrick Laux, Maximilian Schwarz, Pascal Zabré, Stephen Munga, Sammy Khagayi, Ibrahima Diouf, Harald Kunstmann   +11 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source