Results 81 to 90 of about 121,425 (305)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Process‐Based Atmosphere‐Hydrology‐Malaria Modeling: Performance for Spatio‐Temporal Malaria Transmission Dynamics in Sub‐Saharan Africa

Water Resources Research
With the goal of eradication by 2030, Malaria poses a significant health threat, profoundly influenced by meteorological and hydrological conditions. In support of malaria vector control efforts, we present a high‐resolution, coupled physically‐based ...
Mame Diarra Bousso Dieng, Adrian M. Tompkins, Joël Arnault, Ali Sié, Benjamin Fersch, Patrick Laux, Maximilian Schwarz, Pascal Zabré, Stephen Munga, Sammy Khagayi, Ibrahima Diouf, Harald Kunstmann   +11 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Environmental DNA supports importance of heterogeneous pond landscapes for arthropod diversity conservation

Ecosphere
Freshwater ponds host diverse arthropod communities, but conservation frameworks are scarce. Heterogeneous pond mosaics of various sizes and successional stages can develop during raw material extraction in mining sites, acting as refugia for a variety ...
Vera Zizka, Katharina Schwesig, Nele Engel, Norbert Hölzel, Christoph Scherber   +4 more
doaj   +1 more source

Diversity of lakes and ponds in the forest-tundra ecozone: from limnicity to limnodiversity

GIScience & Remote Sensing
Arctic and subarctic landscapes have unique hydrological and limnological features and are now experiencing rapid change due to climate warming and permafrost thaw. The highly abundant lakes, ponds, and rivers across these landscapes play an increasingly
Pedro Freitas, Gonçalo Vieira, Diana Martins, João Canário, Pedro Pina, Birgit Heim, Bennet Juhls, Raoul-Marie Couture, Warwick F. Vincent   +8 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Production of algae from pig wastewaster in high rate ponds

, 1980
Meeting: Workshop on High Rate Algae Ponds, 27-29 Feb.
Lee, B.Y., Dodd, C.
core   +1 more source

Hydrodynamics and Aquatic Vegetation Drive Spatial Patterns of Environmental DNA in Ponds

Environmental DNA
Environmental DNA (eDNA) sampling is a powerful method for detecting aquatic species at low densities. However, eDNA may remain close to the source in lentic systems, decreasing the effectiveness of eDNA surveys.
Sandra R. Mayne, Jeffrey A. Manning, Stephen M. Henderson, Meghan B. Parsley, Katherine M. Strickler, Jeffrey R. Nielson, Caren S. Goldberg   +6 more
doaj   +1 more source

ESTIMATED COSTS AND RETURNS FOR CATFISH FARMS WITH RECIRCULATING PONDS ALONG THE UPPER TEXAS COAST [PDF]

Cost, returns, and economies of scale for small, medium and large catfish farms with recirculating ponds are presented for the upper Texas coast. Internal rates of return are 0.150, 0.183 and 0.219, respectively.
Clary, Gregory M., Griffin, Wade L., Lambregts, Johannes Adrianus, Lacewell, Ronald D., Davis, James T.   +4 more
core