Results 61 to 70 of about 320,389 (303)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Spin projection operators in (A)dS and partial masslessness

Physics Letters B, 2020
We elaborate on the traceless and transverse spin projectors in four-dimensional de Sitter and anti-de Sitter spaces. The poles of these projectors are shown to correspond to partially massless fields.
Sergei M. Kuzenko, Michael Ponds
doaj   +1 more source

Comparison of ecosystem processes in a woodland and prairie pond with different hydroperiods [PDF]

, 2017
Shallow lakes and ponds constitute a significant number of water bodies worldwide. Many are heterotrophic, indicating that they are likely net contributors to global carbon cycling. Climate change is likely to have important impacts on these waterbodies.
Ensley-Field, Mira W., Glasenapp, Matthew R., Goodbar, Ian A., Harman, J. Douglas, Hornbach, Daniel J., Hove, Mark C., Huber, Benjamin D., Kangas, Emily A., Liu, Kira X., Stark-Ragsdale, Molly, Tran, Long K.   +10 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Digitization as one of the methods of assessing the number and distribution of small water bodies

Oceanological and Hydrobiological Studies
Small water bodies (ponds) are a widespread component of the landscape; however, their exact number is often estimated by their small size, temporal variability, or being invisible due to dense vegetation cover.
Golus Włodzimierz, Markowski Maciej
doaj   +1 more source

A Knowledge Discovery in Motion Sickness: A Comprehensive Literature Review

IEEE Access, 2019
Motion sickness is a common perturbation experienced by humans in response to motion stimuli. The motion can happen in either real or virtual environments perceived by the vestibular system and visual illusion. The extensive varieties of research studies
Afsaneh Koohestani, Darius Nahavandi, Houshyar Asadi, Parham M. Kebria, Abbas Khosravi, Roohallah Alizadehsani, Saeid Nahavandi   +6 more
doaj   +1 more source

The spatial and temporal heterogeneity of macrophyte communities in thirty small, temporary ponds over a period of ten years [PDF]

, 2008
Ponds are important habitats within many landscapes because of the diversity of wildlife they support. This arises in part because of the heterogeneity of ecological communities found in neighbouring ponds but this variation has proved difficult to ...
Allen, Andrushchyshyn, Angelibert, Boileau, Boothby, Brian, Briers, Briers, Clarke, De Meester, de Winton, Declerck, Edvardsen, Edvardsen, Fleury, Fortin, Friday, Gibbins, Godwin, Helliwell, Hinden, Jeffries, Jeffries, Jeffries, Jeffries, Jeffries, Joye, Kalin, Kazmierczak, Key, Linton, Matheson, Oertli, Rodwell, Rundle, Sanderson, Scheffer, Sederias, Smouse, Sondergaard, Talling, Urban, Wheeler, Williams, Wilson   +44 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source