Results 191 to 200 of about 158,682 (286)

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

PON [PDF]

, 2019
openaire   +1 more source

Pediatric acute ischemic stroke: unusual presentation with dizziness neurological symptoms in a young child: a case report. [PDF]

Ann Med Surg (Lond)
Adhikari S, Shrestha A, Shrestha H, Pandit A, Koirala M, Rimal S.   +5 more
europepmc   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Global author collaborations in lupus research and publications: a meta-research and network analysis. [PDF]

Lupus Sci Med
Arnaud L, Chasset F, Martin T, Pons-Estel GJ, Piga M.   +4 more
europepmc   +1 more source

Integrated Analysis of HER2 Expression and ERBB2 Alterations in Bladder Cancer

Cancer Science, EarlyView.
Integrated analysis of 445 bladder cancers showed that HER2 membrane expression and ERBB2 amplification are distinct features. HER2 expression overlapped with NECTIN4 expression, whereas ERBB2 amplification was enriched in the LumU subtype and associated with poor prognosis.
Kensuke Hirosuna, Kazuki Nishimura, Moritoshi Sakamoto, Satoshi Tokushige, Keita Nakamori, Tomohisa Matsunaga, Yuki Yoshikawa, Takeshi Tsutsumi, Ryoichi Maenosono, Takuya Tsujino, Masahiko Ajiro, Haruhito Azuma, Akihide Yoshimi, Kazumasa Komura   +13 more
wiley   +1 more source

Atypical MRI presentation of symmetrical thalamic and basal ganglia lesions in adult-onset MOG-IgG-associated disease: a case report. [PDF]

Front Hum Neurosci
Wang Y, Xin Z, Meng R, Zhao Z, Zhu Z.
europepmc   +1 more source

The Social Determination of Racial Inequities in Oral Health Among Indigenous Peoples

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To foster a critical analysis of the racial inequities affecting the oral health (OH) of Indigenous peoples in Brazil, framed by the social determination of the health‐disease‐care process (SDHP). Methods This critical literature review articulates the themes of colonisation, Indigenous peoples' oral health and racial inequities in ...
Lucas Fernando Rodrigues dos Santos, Diego Francisco Lima da Silva, Tainá Faustino Mafra, Herika de Arruda Mauricio, Rafael da Silveira Moreira   +4 more
wiley   +1 more source

Diagnostic Uncertainty in Rapidly Progressive Brainstem Lesions: A Radiological Diagnosis of Probable CNS Relapse of Diffuse Large B-cell Lymphoma. [PDF]

Cureus
Chan YSE, Santhosh Kumar P, Bull T, Ibbeson B.   +3 more
europepmc   +1 more source

A Survey of Methods for Constructing 3D Urban Models From Point Clouds

Computer Graphics Forum, EarlyView.
The survey outlines a general process for constructing 3D models from point clouds and categorizes the methods based on their use of templates, basic surface primitives, hybrid approaches, or linear primitives. Additionally, the survey reviews the datasets and benchmarks that are essential for testing and training the developed methods.
Chiara Romanengo, Silvia Biasotti, Bianca Falcidieno, Daniela Cabiddu, Elia Moscoso Thompson, Michela Spagnuolo   +5 more
wiley   +1 more source