PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation. [PDF]
Mol Cell Biol, 2012 Bobrovnikova-Marjon E +7 more
europepmc +1 more source
Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. [PDF]
Genes Dev, 2007 Aggarwal P +11 more
europepmc +1 more source
Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. [PDF]
Cell Stem Cell, 2007 Ruzankina Y +9 more
europepmc +1 more source
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation. [PDF]
Nature, 2016 Münch C, Harper JW.
europepmc +1 more source
Quantitative Phospho-proteomic Analysis of TNFα/NFκB Signaling Reveals a Role for RIPK1 Phosphorylation in Suppressing Necrotic Cell Death. [PDF]
Mol Cell Proteomics, 2017 Mohideen F +4 more
europepmc +1 more source
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. [PDF]
Cancer Cell, 2010 Aggarwal P +10 more
europepmc +1 more source
The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation. [PDF]
Mol Cell Biol, 2011 Vaites LP +8 more
europepmc +1 more source
Multiplex single-molecule interaction profiling of DNA-barcoded proteins. [PDF]
Nature, 2014 Gu L +5 more
europepmc +1 more source