CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu +13 more
wiley +1 more source
Pool-Boiling Performance on Thin Metal Foils with Graphene-Oxide-Nanoflake Deposit. [PDF]
Bregar T +4 more
europepmc +1 more source
Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram +4 more
wiley +1 more source
Numerical Simulation of Pool Boiling on Novel Microstructured Heated Surface
Improving the pool boiling heat transfer by changing the properties of the heating surface has been experimentally studied by many researchers. In this paper, two novel microstructured surfaces with open channels were simulated and investigated.
Chen Xu +4 more
doaj +1 more source
A Comprehensive Experimental Investigation of Additives to Enhance Pool Boiling Heat Transfer of a Non-Azeotropic Mixture. [PDF]
Xu C, Qian Z, Ren J.
europepmc +1 more source
NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source
Experimental Study of Halloysite Nanofluids in Pool Boiling Heat Transfer. [PDF]
Le Ba T +7 more
europepmc +1 more source
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang +10 more
wiley +1 more source
Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao +10 more
wiley +1 more source
Nanosecond Laser-Textured Copper Surfaces Hydrophobized with Self-Assembled Monolayers for Enhanced Pool Boiling Heat Transfer. [PDF]
Može M +4 more
europepmc +1 more source

