Results 81 to 90 of about 22,361 (257)

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Experimental Research on CO2 Pool Boiling Heat Transfer outside Horizontal Tube

Zhileng xuebao, 2015
The pool boiling heat transfer of natural refrigerant CO2 outside single horizontal tube is investigated experimentally under different boiling pressure.
Liu Shengchun, Li Lan, Ning Jinghong, Liu Jiangbin   +3 more
doaj   +2 more sources

EXPERIMENTAL STUDY OF POOL BOILING OF NANO-FLUIDS

Journal of Engineering and Sustainable Development, 2022
Pool boiling of Nano Al2O3, TiO2, and ZrO2 of concentrations 0.1, 0.4, 1.0, 2.5, 5.0 g/L in distilled water (which is taken as a base fluid) were experimentally studied in a test boiling chamber of stainless steel cylindrical vessel of 15 cm diameter ...
Amer Hameed Majeed, Yasmin Hamed Abd
doaj  

Pool Boiling Heat Transfer Characteristics of SiO₂ and BN Nanoparticles Dispersed Mono and Hybrid Nanofluids. [PDF]

Nanomaterials (Basel), 2023
Ajeeb W, Murshed SMS.
europepmc   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

A Meta-Analysis Review: Nanoparticles as a Gateway to Optimized Boiling Surfaces

Nanomaterials
Pool boiling is essential in many industrial manufacturing applications. In addition, it can become critical in the journey towards improving energy generation efficiency and accomplishing the goal of net-zero carbon emissions by 2050 via new or ...
Giulia Motta, Antonis Sergis
doaj   +1 more source

Laser Treatment of Surfaces for Pool Boiling Heat Transfer Enhancement. [PDF]

Materials (Basel), 2023
Orman ŁJ, Radek N, Pietraszek J, Wojtkowiak J, Szczepaniak M.   +4 more
europepmc   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Pool Boiling Heat Transfer Characteristics of New and Recycled Alumina Nanofluids. [PDF]

Nanomaterials (Basel), 2023
Ajeeb W, Murshed SMS.
europepmc   +1 more source