Results 271 to 280 of about 122,339 (348)
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick +7 more
wiley +1 more source
Three-Dimensional Biphilic Structures Elevating Pool Boiling Heat Transfer
Jiahao Zhao, Xiaolong Yang, Di Zhu
openalex +1 more source
Growth and Variation in Fallow Deer (Dama dama L.) From Two Contrasting Habitats in Southern Britain
ABSTRACT We have compiled a unique data set on the age, sex, body weight and dimensions of over 500 European fallow deer from two contrasting areas of habitat in southern England: a high‐density managed parkland population and a lower‐density feral woodland one.
Adrian M. Lister, Norma G. Chapman
wiley +1 more source
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
Interactive Groupwise Comparison for Reinforcement Learning from Human Feedback
The standard RLHF uses pairwise comparisons and therefore requires a large number of comparisons leading to a high workload. The comparison pairs are suggested by the system and cannot be chosen by the user. Our RLHF approach provides more agency to the user and demands less work: we leverage the user's visual abilities to effectively explore the ...
Jan Kompatscher +4 more
wiley +1 more source
Dissection of Mitochondrial Function via Chemical Perturbation and Single‐Cell Profiling
We establish a systematic framework to dissect mitochondrial function at the module level by combining targeted chemical perturbations with scRNA‐seq. This approach reveals shared and module‐specific programs linking mitochondrial activity to mito‐nuclear communication, stress response, and cell cycle, highlighting the tight coupling between ...
Hao Luo +4 more
wiley +1 more source
Perspectives of parents of children with Dravet syndrome indicate that extreme heat and high temperatures exacerbate epileptic seizures, introduce new seizure triggers, and require the adoption of specific seizure‑management strategies. Abstract Aim To describe parental perspectives on how heatwaves and high ambient temperatures influence seizure ...
Angel Aledo‐Serrano +8 more
wiley +1 more source
Leadership and Accountability in Faith‐Based Institutions: Evidence From UK Mosques
ABSTRACT This study investigates accountability in religious institutions on the basis of evidence obtained from interviews with relevant parties in UK mosques. We mobilize prior theoretical contention regarding servant leadership and constraints on personal accountability to expose perceptions of seriously deficient discharge outcomes.
Umair Riaz +3 more
wiley +1 more source

