Results 281 to 290 of about 122,339 (348)

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

open access: yesThe FEBS Journal, EarlyView.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu   +9 more
wiley   +1 more source

Modeling of Bead-on-Plate Laser Beam Melting Using Innovative Laser with a Single-Mode Core Surrounded by a Multimode Ring. [PDF]

open access: yesMaterials (Basel)
Kubiak M   +6 more
europepmc   +1 more source

Theatres of Indirectness: Passive Aggression and Failure

open access: yes
Critical Quarterly, EarlyView.
Sara Crangle, Sam Ladkin
wiley   +1 more source

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