Results 211 to 220 of about 144,761 (305)
Novel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability. [PDF]
Int J Nanomedicine, 2016 Guo S, Pham K, Li D, Penzak SR, Dong X.
europepmc +1 more source
Decoupling Dynamics and Crosslink Stability in Supramolecular Hydrogels Using Associative Exchange
Advanced Materials, EarlyView.How does reorganization impact the stability of supramolecular hydrogels? In contrast to dissociative crosslink exchange, implementing associative exchange in macroscale DNA hydrogels enables decoupling of reorganization dynamics from thermal and mechanical stability.
Pierre Le Bourdonnec +4 more
wiley +1 more source
Development and characterization of mixed niosomes for oral delivery using candesartan cilexetil as a model poorly water-soluble drug. [PDF]
AAPS PharmSciTech, 2015 Sezgin-Bayindir Z, Antep MN, Yuksel N.
europepmc +1 more source
A Biochar‐Based Composite Hydrogel Microenvironment for Enhanced Biocatalysis
Advanced Materials, EarlyView.This work presents the synthesis of a polyacrylamide hydrogel wherein biomass‐derived biochar is co‐encapsulated with the enzyme horseradish peroxidase (HRP). The resulting composite hydrogel possesses balanced electron‐rich and electron‐deficient domains, creating an optimal microenvironment that concentrates both hydrogen peroxide and phenol ...
Shengzhe Wang +9 more
wiley +1 more source
Oral nanomedicines for the treatment of parasitic diseases [PDF]
, 2014 Dea Ayuela, Maria Auxiliadora +3 more
core +1 more source
Advanced Materials, EarlyView.A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim +9 more
wiley +1 more source
Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation
Advanced Materials, EarlyView.Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju +7 more
wiley +1 more source
Advanced Materials, EarlyView.ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu +8 more
wiley +1 more source
Two‐Photon 3D Printing of Functional Microstructures Inside Living Cells
Advanced Materials, EarlyView.This study demonstrates 3D printing inside living cells by using two‐photon photo‐lithography. A bio‐compatible photoresist is injected into cells and selectively polymerized with a femtosecond laser, creating custom‐shaped intracellular structures with submicron resolution.
Maruša Mur +4 more
wiley +1 more source