Results 41 to 50 of about 19,805 (199)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Equilibrium Modeling Study on Thermal Treatment of POPs
为利用等离子体处理持续有机污染物POPs,需要根据某些已有的POPs数据判断其对于各类POPs的销毁能力。基于 Gibbs 自由能最小原理和能量守恒原理建立了平衡计算模型,并与实验结果进行对照。结果表明,模型在给定有机废物组分和产物温度的情况下与实验结果符合较好。利用该模型模拟了加水量对等离子体温度区域范围内处理数种 POPs 的平衡产物,以及不同温度下的摧毁率。该方法可用于预测采用等离子体技术处理各种 POPs ...
田君国 +5 more
core +2 more sources
Partitioning of Persistent Organic Pollutants between Adipose Tissue and Serum in Human Studies
Blood is the most widely used matrix for biomonitoring of persistent organic pollutants (POPs). It is assumed that POPs are homogenously distributed within body lipids at steady state; however, the variability underlying the partitioning of POPs between ...
Meg-Anne Moriceau +8 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
2, 2’, 4, 4’-tetrabromodiphenyl ether (BDE-47), one of the most abundant and toxic congeners of polybrominated diphenyl ethers (PBDEs), has been implicated in thyroid disorders, but its thyroid toxicity in human thyroid cells and underlying mechanisms ...
Guangshan Xie +3 more
doaj +1 more source
In this study, a comprehensive investigation was performed to understand the overall occurrence, relative distribution, and bioaccumulation of seven different groups of POPs, comprising 27 polybrominated diphenyl ethers (PBDEs), 76 polychlorinated ...
Gyojin Choo +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Persistent organic pollutants (POPs) may affect the immune system of seabirds, and some field studies have examined this effect. There are evidences that POPs cause negative effects on the immune system, but in Antarctic penguins data are scarce.
Solange Jara +5 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

