Results 101 to 110 of about 6,918,483 (191)
A Genomewide Admixture Mapping Panel for Hispanic/Latino Populations [PDF]
The American Journal of Human Genetics, 2007 Admixture mapping (AM) is a promising method for the identification of genetic risk factors for complex traits and diseases showing prevalence differences among populations. Efficient application of this method requires the use of a genomewide panel of ancestry-informative markers (AIMs) to infer the population of origin of chromosomal regions in ...
Mao, Xianyun +11 more
openaire +2 more sources
Assortative mating by population of origin in a mechanistic model of admixture
bioRxiv, 2019 Populations whose mating pairs have levels of similarity in phenotypes or genotypes that differ systematically from the level expected under random mating are described as experiencing assortative mating.
Amy Goldberg +2 more
semanticscholar +1 more source
Recent Admixture in an Indian Population of African Ancestry [PDF]
The American Journal of Human Genetics, 2011 Identification and study of genetic variation in recently admixed populations not only provides insight into historical population events but also is a powerful approach for mapping disease loci. We studied a population (OG-W-IP) that is of African-Indian origin and has resided in the western part of India for 500 years; members of this population are ...
Ankita, Narang +7 more
openaire +3 more sources
Calculating expected DNA remnants from ancient founding events in human population genetics
BMC Genetics, 2008 Background Recent advancements in sequencing and computational technologies have led to rapid generation and analysis of high quality genetic data.
Stacey Andrew +2 more
doaj +1 more source
Molecular biology and evolution, 2017 Hybridization is a natural or anthropogenic process that can deeply affect the genetic make-up of populations, possibly decreasing individual fitness but sometimes favoring local adaptations.
M. Galaverni +5 more
semanticscholar +1 more source
The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs
Human Genomics, 2004 Understanding the nature of evolutionary relationships among persons and populations is important for the efficient application of genome science to biomedical research.
Shriver Mark D +7 more
doaj +1 more source
4513 European Ancestry as a Risk Factor for Atrial Fibrillation in Puerto Rican Hispanics
Journal of Clinical and Translational Science, 2020 OBJECTIVES/GOALS: Atrial fibrillation (AF) not only is the most common sustained cardiac arrhythmia in clinical practice placing patients at increased risk for thromboembolic events.
Ariel Gonzalez-Cordero
doaj +1 more source
A Spatial Framework for Understanding Population Structure and Admixture [PDF]
PLOS Genetics, 2015 Geographic patterns of genetic variation within modern populations, produced by complex histories of migration, can be difficult to infer and visually summarize. A general consequence of geographically limited dispersal is that samples from nearby locations tend to be more closely related than samples from distant locations, and so genetic covariance ...
Bradburd, Gideon +2 more
openaire +5 more sources
Animal Genetics, 2018 Summary Uganda has a large population of goats, predominantly from indigenous breeds reared in diverse production systems, whose existence is threatened by crossbreeding with exotic Boer goats.
R. Onzima +5 more
semanticscholar +1 more source
Using population admixture to help complete maps of the human genome
Nature Genetics, 2013 Tens of millions of base pairs of euchromatic human genome sequence, including many protein-coding genes, have no known location in the human genome. We describe an approach for localizing the human genome's missing pieces using the patterns of genome ...
G. Genovese +12 more
semanticscholar +1 more source