Results 121 to 130 of about 559,488 (309)

Pension reform in a rapidly ageing country: the case of Ukraine [PDF]

open access: yes
Ukraine has a rapidly ageing and declining population. A dynamic forward-looking Computable General Equilibrium(CGE)model with an explicitly modelled Pay-As-You-­Go pension scheme is constructed to perform simulations of different pension reform ...
Katerina Lisenkova
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Actuarial neutrality across generations applied to public pensions under population ageing: effects on government finances and national saving [PDF]

open access: yes
In welfare states, collective saving has declined to a persistently negative level, while reduced fertility and increasing longevity are leading to increasing pension liabilities.
Heikki Oksanen
core   +3 more sources

The Impact of Population Ageing: A Review. [PDF]

open access: yesIran J Public Health, 2021
Ismail Z   +3 more
europepmc   +1 more source

Immigration and growth in an ageing economy [PDF]

open access: yes
This paper argues that immigration can help to alleviate the burden ageing presents for the welfare states of most Western Economies. We develop a macroeconomic framework which deals with the impact of both ageing and immigration on economic growth. This
Muysken, Joan, Ziesemer, Thomas
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Ageing society issues in Korea

open access: yes, 2007
Population ageing is a social phenomenon not only in developed countries but also in developing countries. The rapidity of population ageing in Korea during the past decade epitomizes how rapidly developing countries are ageing compared to developed ...
CHOI, Sung Jao
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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