Results 1 to 10 of about 620,340 (120)
BMC Public Health, 2021 Background The long-term growth and sustained high prevalence of obesity in the US is likely to increase the burden of Type 2 diabetes. Hispanic individuals are particularly burdened by a larger share of diabetes than non-Hispanic White individuals ...
Matthew Lee Smith +4 more
doaj +1 more source
Forecasting prevalence and mortality of Alzheimer's disease using the partitioning models
Experimental Gerontology, 2023 Objectives: Health forecasting is an important aspect of ensuring that the health system can effectively respond to the changing epidemiological environment.
I. Akushevich +5 more
doaj +1 more source
Immunity & Ageing, 2023 Background Frailty, a clinical syndrome commencing at midlife, is a risk for morbidity and mortality. Little is known about the factors that contribute to the chronic inflammatory state associated with frailty.
Anjali M. Byappanahalli +6 more
doaj +1 more source
Association of extracellular vesicle inflammatory proteins and mortality
Scientific Reports, 2022 Even before the COVID-19 pandemic declines in life expectancy in the United States were attributed to increased mortality rates in midlife adults across racial and ethnic groups, indicating a need for markers to identify individuals at risk for early ...
Nicole Noren Hooten +6 more
doaj +1 more source
Sex-specific transcriptome differences in a middle-aged frailty cohort
BMC Geriatrics, 2022 Background Frailty is a clinical syndrome described as reduced physiological reserve and increased vulnerability. Typically examined in older adults, recent work shows frailty occurs in middle-aged individuals and is associated with increased mortality ...
Natasha L. Pacheco +8 more
doaj +1 more source
Journal of Translational Medicine, 2020 Background Inflammation-related atherosclerotic peripheral vascular disease is a major end organ complication of diabetes mellitus that results in devastating morbidity and mortality.
Sharon F. Wu +5 more
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Inflammatory proteins are associated with mortality in a middle‐aged diverse cohort
Clinical and Translational Medicine, 2023 Background Recent data indicate a decline in overall longevity in the United States. Even prior to the COVID‐19 pandemic, an increase in midlife mortality rates had been reported. Life expectancy disparities have persisted in the United States for racial
Nicole Noren Hooten +5 more
doaj +1 more source
Race, APOE genotypes, and cognitive decline among middle-aged urban adults
Alzheimer’s Research & Therapy, 2021 Background Associations of Apolipoprotein (APOE) ε2 or ε4 (APOE2 or APOE4) dosages with cognitive change may differ across racial groups. Methods Longitudinal data on 1770 middle-aged White and African American adults was compiled from the Healthy Aging ...
May A. Beydoun +7 more
doaj +1 more source
Plasma gelsolin levels are associated with diabetes, sex, race, and poverty
Journal of Translational Medicine, 2023 Background The growing epidemic of the inflammation-related metabolic disease, type 2 diabetes mellitus, presents a challenge to improve our understanding of potential mechanisms or biomarkers to prevent or better control this age-associated disease.
Nicole Noren Hooten +8 more
doaj +1 more source
SSM: Population Health, 2022 A sizeable literature documents the associations between adverse childhood experiences (ACEs) and poor health in later life. By and large, ACEs are measured using retrospective self-reports.
Etienne Breton +4 more
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