Results 21 to 30 of about 704,078 (308)

Population Aging and Economic Growth in EU Member States

open access: yes, 2021
The improvements in economic development, living standards, and the health sector have raised the life expectancy on the world. The rising life expectancy together with decreasing fertility rates have led to population aging.
Yilmaz Bayar   +3 more
core   +1 more source

Hospital-treated prevalent infections, the plasma proteome and incident dementia among UK older adults

open access: yesiScience, 2023
Summary: The plasma proteome can mediate the association of hospital-treated infections with dementia incidence. We screened up to 37,269 UK Biobank participants aged 50–74 years for the presence of a prevalent hospital-treated infection, subsequently ...
May A. Beydoun   +10 more
doaj   +1 more source

Validation of the JEN frailty index in the National Long-Term Care Survey community population: identifying functionally impaired older adults from claims data

open access: yesBMC Health Services Research, 2018
Background Use of a claims-based index to identify persons with physical function impairment and at risk for long-term institutionalization would facilitate population health and comparative effectiveness research.
Bruce Kinosian   +5 more
doaj   +1 more source

Pathways explaining racial/ethnic and socio-economic disparities in incident all-cause dementia among older US adults across income groups

open access: yesTranslational Psychiatry, 2022
Differential racial and socioeconomic disparities in dementia incidence across income groups and their underlying mechanisms remain largely unknown. A retrospective cohort study examining all-cause dementia incidence across income groups was conducted ...
May A. Beydoun   +5 more
doaj   +1 more source

Sleep in the Aging Population [PDF]

open access: yesSleep Medicine Clinics, 2017
There are normal changes to sleep architecture throughout the lifespan. There is not, however, a decreased need for sleep and sleep disturbance is not an inherent part of the aging process. Sleep disturbance is common in older adults because aging is associated with an increasing prevalence of multimorbidity, polypharmacy, psychosocial factors ...
Brienne, Miner, Meir H, Kryger
openaire   +3 more sources

Cognitive life expectancy by educational attainment in Mexican adults aged 60 and older

open access: yesSalud Pública de México, 2023
Objective. To estimate cognitively healthy life expectancy (CHLE), cognitive impairment life expectancy (CILE), and dementia life expectancy (DLE) in Mexican adults aged 60 and older stratified by educational attainment. Materials and methods.
José Eduardo Cabrero-Castro   +3 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Elevated neutrophil-to-lymphocyte ratio and the incidence of autoimmune diseases: evidence from a large prospective cohort study

open access: yesScientific Reports
We prospectively assessed the association between neutrophil-to-lymphocyte ratio (NLR) and incident autoimmune disease risk using data from 430,347 UK Biobank participants recruited between 2006 and 2010.
Dongwon Yoon   +5 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

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