Results 61 to 70 of about 704,078 (308)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Extracellular vesicle mitochondrial DNA levels are associated with race and mitochondrial DNA haplogroup

iScience
Summary: Circulating cell-free mitochondrial DNA (ccf-mtDNA) acts as a damage-associated molecular pattern molecule and may be cargo within extracellular vesicles (EVs).
Anjali M. Byappanahalli, Victor Omoniyi, Nicole Noren Hooten, Jessica T. Smith, Nicolle A. Mode, Ngozi Ezike, Alan B. Zonderman, Michele K. Evans   +7 more
doaj   +1 more source

Support practices by an interdisciplinary team in a palliative-care unit for relatives of patients in agonal phase

BMC Palliative Care, 2020
Background In the absence of extant recommendations, the aim of this study was to formalise support practices used by an interdisciplinary team in a palliative-care unit (PCU) for the relatives of patients in the agonal phase preceding death.
M. Mélin, H. Amieva, M. Frasca, C. Ouvrard, V. Berger, H. Hoarau, C. Roumiguière, B. Paternostre, N. Stadelmaier, N. Raoux, V. Bergua, B. Burucoa   +11 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Epigenetic aging markers in the association between frailty and mortality among U.S. adults

BMC Medicine
Background Frailty reflects diminished physiological reserve and increased vulnerability to adverse health outcomes. It has been linked to biological aging, including epigenetic age acceleration (EAA), a DNA methylation–based marker of aging, but the ...
May A. Beydoun, Nicole Noren Hooten, Hind A. Beydoun, Michael F. Georgescu, Jack Tsai, Michele K. Evans, Alan B. Zonderman   +6 more
doaj   +1 more source

Sarcopenic obesity and the incidence and progression of cardiometabolic multimorbidity: A longitudinal cohort analysis from the CHARLS study

Experimental Gerontology
Objective: This study aimed to explore the association between sarcopenic obesity (SO) and the incidence and progression of cardiometabolic multimorbidity (CMM) in a Chinese population.
Xinyue Wei, Shuai Guo, Jiatong Gao, Xiaonan Shi, Binbin Su, Zuliyaer Talifu, Xiaoying Zheng   +6 more
doaj   +1 more source

“Toxic” schools? How school exposures during adolescence influence trajectories of health through young adulthood

SSM: Population Health, 2020
A large body of research identifies the critical role of early-life social contexts such as neighborhoods and households in shaping life course trajectories of health.
Courtney E. Boen, Karen Kozlowski, Karolyn D. Tyson   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

EGYPT - AGEING POPULATION

The Egyptian Journal of Geriatrics and Gerontology, 2014
Background: The term "frailty" has been used clinically as a global concept to describe a condition, common in the old, of impaired strength, endurance, and balance, vulnerability to trauma and other stressors, and high risk for morbidity, disability, and mortality.
Hala S. Sweed, Manar M. Maemon
openaire   +1 more source

Population Aging: Facts, Challenges, and Responses [PDF]

The world’s population is growing older, leading us into uncharted demographic waters. There will be higher absolute numbers of elderly people, a larger share of elderly, longer healthy life expectancies, and relatively fewer numbers of working-age ...
Axel Boersch-Supan, Atsushi Seike, David E. Bloom, Patrick McGee   +3 more
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