Results 111 to 120 of about 615,397 (308)

A Monodisperse Population Balance Model for Nanoparticle Agglomeration in the Transition Regime. [PDF]

Materials (Basel), 2021
Kelesidis GA, Kholghy MR.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Model reliability of multi-dimensional population balance models for crystallization [abstract] [PDF]

, 2016
Model reliability of multi-dimensional population balance models for crystallization ...
Zoltan Nagy (1254105), Chris Rielly (1254369), Akos Borsos (2816020), Brahim Benyahia (1258056), Dimitris Fysikopoulos (1249971)   +4 more
core   +1 more source

Improvement of a 1D Population Balance Model for Twin-Screw Wet Granulation by Using Identifiability Analysis. [PDF]

Pharmaceutics, 2021
Barrera Jiménez AA, Van Hauwermeiren D, Peeters M, De Beer T, Nopens I.   +4 more
europepmc   +1 more source

Comparison of Implicit-Texture and Population-Balance Foam Models

SPE EOR Conference at Oil and Gas West Asia, 2016
Abstract Simulation models for foam enhanced oil recovery are of two types: those that treat foam texture or bubble size explicitly (population-balance models) and those that treat the effects of foam texture implicitly through a gas mobility-reduction factor.
Lotfollahi, Mohammad, Farajzadeh, Rouhi, Delshad, Mojdeh, Varavei, Abdoljalil, Rossen, William R.   +4 more
openaire   +4 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Predicting the population dynamics of the house dust mite 'Dermatophagoides pteronyssinus' (Acari: pyroglyphidae) in response to a constant hygrothermal environment using a model of the mite life cycle [PDF]

, 2007
A generalised model of the life cycle of a house dust mite, which can be tailored to any particular species of domestic mite, is presented. The model takes into account the effects of hygrothermal conditions on each life cycle phase.
Pretlove, Stephen, Ucci, M, Crowther, David, Biddulph, P, Ridley, Iab, Ucci, Mcarcella, Oreszczyn, Tadj, Leung, B, Ridley, I, Crowther, D, Oreszczyn, T, Leung, Brian, Pretlove, S, Hart, B, Biddulph, Phillip, Wilkinson, T, Hart, Barbara, Wilkinson, Toby   +17 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

In-Depth Understanding of the Impact of Material Properties on the Performance of Jet Milling of Active Pharmaceutical Ingredients

Pharmaceutics
Background/Objectives: Among different milling techniques, spiral air jet milling can produce finer particles without the use of solvents or additives, thereby improving the bioavailability and content uniformity of the final dosage form.
Viktor Bultereys, Kensaku Matsunami, Laure Descamps, Roel Mertens, Alain Collas, Ashish Kumar   +5 more
doaj   +1 more source