Results 141 to 150 of about 615,397 (308)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Population Balance Modeling and Opinion Dynamics—A Mutually Beneficial Liaison?

, 2018
In this contribution, we aim to show that opinion dynamics and population balance modeling can benefit from an exchange of problems and methods. To support this claim, the Deffuant-Weisbuch model, a classical approach in opinion dynamics, is formulated ...
Michael Kuhn, Christoph Kirse, Heiko Briesen   +2 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A three-dimensional population balance model of granulation with a mechanistic representation of the nucleation and aggregation phenomena

, 2008
A comprehensive model is discussed for wet granulation based on a three-dimensional population balance, as an attempt to capture particle-level phenomena and their influence on the population-level behaviour.
Immanuel, Charles D., Poon, Jonathan M.-H., Doyle, III, Francis J., Litster, James D.   +3 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Parameter identification, reliability and model discrimination of population balance models for crystallization [Poster]

, 2016
Parameter identification, reliability and model discrimination of population balance models for crystallization ...
Zoltan Nagy (1254105), Chris Rielly (1254369), Akos Borsos (2816020), Brahim Benyahia (1258056), Dimitris Fysikopoulos (1249971)   +4 more
core   +1 more source

Parametric study of population balance model on the DEBORA flow boiling experiment

Nuclear Engineering and Technology
In two-fluid simulations of flow boiling, the modeling of the mean bubble diameter is a key parameter in the closure relations governing the intefacial transfer of mass, momentum, and energy.
Aljoša Gajšek, Matej Tekavčič, Boštjan Končar   +2 more
doaj   +1 more source

Polymer flocculation of calcite: Population balance model

, 2006
A population balance (PB) model is used to describe the aggregation/breakage kinetics of calcite flocculation in turbulent pipe flow. The model describes simultaneous aggregation and breakage, and accounts for likely process variables: fluid shear ...
Heath, A.R., Bahri, P.A., Farrow, J.B., Fawell, P.D.   +3 more
core  

Computational simulation of convective boiling using population balance model

, 2022
V magistrskem delu so predstavljeni rezultati simulacije konvektivnega vrenja v navpičnem kanalu, ki smo jih izvedli s programom za računalniško dinamiko tekočin ANSYS Fluent.
Gajšek, Aljoša
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source