Results 61 to 70 of about 2,237,045 (249)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Numerical Simulation of Droplet Breakup and Coalescence in Liquid-liquid Separation Hydrocyclone
Shiyou jixie, 2017 In order to study the breakup and coalescence of droplets in hydrocyclone and their effects on separation performance, the Euler-Euler multiphase flow model and the RSM turbulence model were used to simulate the separation of oil and water in the cyclone.
吕凤霞 +4 more
doaj
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Effect of Oil Droplet Coalescence and Breakup Behavior on Separation Performance of Hydrocyclone
Shiyou jixie, 2019 To study the effects of coalescence and breakup behavior of discrete phase oil droplet on the internal flow field characteristics and separation performance of oil-water separation hydrocyclone, taking the axial guide cone hydrocyclone as study object ...
Li Feng +4 more
doaj
A tale of two cities: Annapolis and St. Augustine balancing preservation and community values in an era of rising seas [PDF]
, 2020 Annapolis, Maryland, and St. Augustine, Florida, are colonial cities on the East Coast of the United States with national historic landmark designations recognizing the strong blends of natural and cultural resources that make each community unique ...
Craig, Lisa M., Keys, Leslee F.
core
Gamma-rays from Galactic Black Hole Candidates with Stochastic Particle Acceleration [PDF]
, 1996 We consider stochastic particle acceleration in plasmas around stellar mass black holes to explain the emissions above 1 MeV from Galactic black hole candidates.
Achterberg A. +12 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Modeling and Simulation of Kuhni Extraction Column Using a Rate-based Model [PDF]
Iranian Journal of Oil & Gas Science and Technology, 2016 In this study, liquid-liquid extraction process in a Kuhni extraction column was modeled and simulated. A non-equilibrium dynamic model was developed for modeling liquid-liquid extraction processes based on a rate-based model.
Amir Hosein Tahershamsi +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source